ArticleBMC genomics2017
Role of the GRAS transcription factor ATA/RAM1 in the transcriptional reprogramming of arbuscular mycorrhiza in Petunia hybrida.
Article in BMC genomics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.
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32 citing papers in PubMed, 62 citations in OpenAlex.
- Spatiotemporal regulation of arbuscular mycorrhizal symbiosis at cellular resolution.The Plant cell · 2026Article
- Article
- Genome-Wide Identification of DlGRAS Family and Functional Analysis ofInternational journal of molecular sciences · 2025Article
- Genome-wide identification of theFrontiers in plant science · 2025Article
- Review
- A dual regulatory role for the arbuscular mycorrhizal master regulator RAM1 in tomato.Journal of experimental botany · 2024Article
- RAM1 orchestrates arbuscular mycorrhizal symbiosis in non-legumes.Journal of experimental botany · 2024Article
- The receptor-like kinase ARK controls symbiotic balance across land plants.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- GRAS gene family in rye (Secale cereale L.): genome-wide identification, phylogeny, evolutionary expansion and expression analyses.BMC plant biology · 2024Article
- Analysis of the molecular and biochemical mechanisms involved in the symbiotic relationship betweenFrontiers in plant science · 2023Article
- Multifaceted roles of GRAS transcription factors in growth and stress responses in plants.iScience · 2022Review
- Molecular Regulation of Arbuscular Mycorrhizal Symbiosis.International journal of molecular sciences · 2022Review
- Integrative Analysis of theFrontiers in plant science · 2022Article
- Multifarious and Interactive Roles of GRAS Transcription Factors During Arbuscular Mycorrhiza Development.Frontiers in plant science · 2022Review
- Overexpression ofFrontiers in plant science · 2022Article
- Phosphate Suppression of Arbuscular Mycorrhizal Symbiosis Involves Gibberellic Acid Signaling.Plant & cell physiology · 2021Article
- Conservation and Diversity in Gibberellin-Mediated Transcriptional Responses Among Host Plants Forming Distinct Arbuscular Mycorrhizal Morphotypes.Frontiers in plant science · 2021Article
- TheFrontiers in plant science · 2021Article
- Constitutive Overexpression ofPlant physiology · 2020Article
- Mechanisms and Impact of Symbiotic Phosphate Acquisition.Cold Spring Harbor perspectives in biology · 2019Review
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Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundDevelopment of arbuscular mycorrhiza (AM) requires a fundamental reprogramming of root cells for symbiosis. This involves the induction of hundreds of genes in the host. A recently identified GRAS-type transcription factor in Petunia hybrida, ATA/RAM1, is required for the induction of host genes during AM, and for morphogenesis of the fungal endosymbiont. To better understand the role of RAM1 in symbiosis, we set out to identify all genes that depend on activation by RAM1 in mycorrhizal roots.
resultsWe have carried out a transcript profiling experiment by RNAseq of mycorrhizal plants vs. non-mycorrhizal controls in wild type and ram1 mutants. The results show that the expression of early genes required for AM, such as the strigolactone biosynthetic genes and the common symbiosis signalling genes, is independent of RAM1. In contrast, genes that are involved at later stages of symbiosis, for example for nutrient exchange in cortex cells, require RAM1 for induction. RAM1 itself is highly induced in mycorrhizal roots together with many other transcription factors, in particular GRAS proteins.
conclusionSince RAM1 has previously been shown to be directly activated by the common symbiosis signalling pathway through CYCLOPS, we conclude that it acts as an early transcriptional switch that induces many AM-related genes, among them genes that are essential for the development of arbuscules, such as STR, STR2, RAM2, and PT4, besides hundreds of additional RAM1-dependent genes the role of which in symbiosis remains to be explored. Taken together, these results indicate that the defect in the morphogenesis of the fungal arbuscules in ram1 mutants may be an indirect consequence of functional defects in the host, which interfere with nutrient exchange and possibly other functions on which the fungus depends.
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