Evidence map›Paper›PMID 28789349›Full record

ArticleOncology letters2017

CD44

Lei Wang, Pengping Li, Wei Hu, Youyou Xia, Chenxi Hu, Liang Liu, Xiaodong Jiang

Open access · diamondAbstract read
In one paragraph

Article in Oncology letters, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 16 citations in OpenAlex.

  1. Review
  2. Article
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  10. Role of metabolism in cancer cell radioresistance and radiosensitization methods.Journal of experimental & clinical cancer research : CR · 2018
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Lei WangDepartment of Radiation Oncology, Lianyungang First People's Hospital, Lianyugang, Jiangsu 222002, P.R. China.
Pengping LiDepartment of Bioinformatics, School of Basic Medical Sciences, Nanjing Medical University, Nanjing, Jiangsu 210029, P.R. China.
Wei HuDepartment of Hepatobiliary Surgery, Lianyungang First People's Hospital, Lianyungang, Jiangsu 222002, P.R. China.
Youyou XiaDepartment of Radiation Oncology, Lianyungang First People's Hospital, Lianyugang, Jiangsu 222002, P.R. China.
Chenxi HuDepartment of Radiation Oncology, Lianyungang First People's Hospital, Lianyugang, Jiangsu 222002, P.R. China.
Liang LiuDepartment of Radiation Oncology, Lianyungang First People's Hospital, Lianyugang, Jiangsu 222002, P.R. China.
Xiaodong JiangDepartment of Radiation Oncology, Lianyungang First People's Hospital, Lianyugang, Jiangsu 222002, P.R. China.
The First People’s Hospital of Lianyungang · CNNanjing Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Emerging evidence has suggested that pancreatic adenocarcinoma is sustained by pancreatic cancer stem cells. The present study aimed to investigate the expression patterns of the pancreatic cancer stem cell surface markers cluster of differentiation CD44 and CD24 in a pancreatic adenocarcinoma cell line, and to investigate the possible mechanisms for their radiation resistance. Flow cytometry was used to analyze the expression patterns of CD44 and CD24 in the pancreatic adenocarcinoma PANC-1 cell line. In addition, a multi-target click model was used to fit cell survival curves and determine the sensitizer enhancement ratio. The apoptosis and cycle distribution of the four cell subsets was determined using flow cytometry, and the level of reactive oxygen species (ROS) was determined using the 2',7'-dichlorofluorescin diacetate probe. The present results identified that the ratios of CD44

Indexed as

PANC-1pancreatic adenocarcinomaradiosensitivityreactive oxygen speciesstem cell

Identifiers

PMID28789349
PMCPMC5529798
OpenAlexW2620558854

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.