ArticleMaterials (Basel, Switzerland)2014
Biocompatibility and Surface Properties of TiO₂ Thin Films Deposited by DC Magnetron Sputtering.
Article in Materials (Basel, Switzerland), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 81 citations in OpenAlex.
- Article
- Synthesis of the Titanium Oxides Using a New Microwave Discharge Method.International journal of molecular sciences · 2025Article
- Advancements in Surface Modification of NiTi Alloys for Orthopedic Implants: Focus on Low-Temperature Glow Discharge Plasma Oxidation Techniques.International journal of molecular sciences · 2025Review
- WATER PLASMA TREATMENT METHOD: SIMULTANEOUS STERILIZATION AND SURFACE MODIFICATION OF TITANIUM-BASED IMPLANTS.Materials research (Sao Carlos, Sao Paulo, Brazil) · 2025Article
- Integral Algorithms to Evaluate TiOInternational journal of molecular sciences · 2022Article
- Biocompatibility of Titanium Oxynitride Coatings Deposited by Reactive Magnetron Sputtering.Bulletin of experimental biology and medicine · 2022Article
- Blood Coagulation on Titanium Dioxide Films with Various Crystal Structures on Titanium Implant Surfaces.Cells · 2022Article
- Effect of Treated Time of Hydrothermal Etching Process on Oxide Layer Formation and Its Antibacterial Properties.Biomimetics (Basel, Switzerland) · 2022Article
- PLGA-Based Composites for Various Biomedical Applications.International journal of molecular sciences · 2022Review
- Anatase Incorporation to Bioactive Scaffolds Based on Salmon Gelatin and Its Effects on Muscle Cell Growth.Polymers · 2020Article
- Effect of the Thickness of TiOMaterials (Basel, Switzerland) · 2020Article
- Titanium surface bio-functionalization using osteogenic peptides: Surface chemistry, biocompatibility, corrosion and tribocorrosion aspects.Journal of the mechanical behavior of biomedical materials · 2018Article
- TiOFrontiers in chemistry · 2018Article
- The Bioactivity and Photocatalytic Properties of Titania Nanotube Coatings Produced with the Use of the Low-Potential Anodization of Ti6Al4V Alloy Surface.Nanomaterials (Basel, Switzerland) · 2017Article
- Atomic layer deposition of nano-TiOInternational journal of nanomedicine · 2017Article
- Cytotoxicity Evaluation of Anatase and Rutile TiO₂ Thin Films on CHO-K1 Cells in Vitro.Materials (Basel, Switzerland) · 2016Article
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Authors and funding
8 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We present the study of the biocompatibility and surface properties of titanium dioxide (TiO₂) thin films deposited by direct current magnetron sputtering. These films are deposited on a quartz substrate at room temperature and annealed with different temperatures (100, 300, 500, 800 and 1100 °C). The biocompatibility of the TiO₂ thin films is analyzed using primary cultures of dorsal root ganglion (DRG) of Wistar rats, whose neurons are incubated on the TiO₂ thin films and on a control substrate during 18 to 24 h. These neurons are activated by electrical stimuli and its ionic currents and action potential activity recorded. Through X-ray diffraction (XRD), the surface of TiO₂ thin films showed a good quality, homogeneity and roughness. The XRD results showed the anatase to rutile phase transition in TiO₂ thin films at temperatures between 500 and 1100 °C. This phase had a grain size from 15 to 38 nm, which allowed a suitable structural and crystal phase stability of the TiO₂ thin films for low and high temperature. The biocompatibility experiments of these films indicated that they were appropriated for culture of living neurons which displayed normal electrical behavior.
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