Evidence map›Paper›PMID 28788073›Full record

ArticleMolecules (Basel, Switzerland)2017

Extracts Obtained from Pterocarpus angolensis DC and Ziziphus mucronata Exhibit Antiplasmodial Activity and Inhibit Heat Shock Protein 70 (Hsp70) Function.

Tawanda Zininga, Chinedu P Anokwuru, Muendi T Sigidi, Milingoni P Tshisikhawe, Isaiah I D Ramaite, Afsatou N Traoré, Heinrich Hoppe, Addmore Shonhai, Natasha Potgieter

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecules (Basel, Switzerland), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.7field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 23 citations in OpenAlex.

  1. Review
  2. Microorganisms · 2025
    Article
  3. Phytochemicals fromPlants (Basel, Switzerland) · 2024
    Article
  4. Frontiers in cell and developmental biology · 2022
    Review
  5. Article
  6. Molecules (Basel, Switzerland) · 2020
    Article
  7. Heliyon · 2020
    Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Tawanda ZiningaBiochemistry Department, School of Mathematical and Natural Sciences, University of Venda, Private Bag X5050, 0950 Thohoyandou, South Africa. tzininga@gmail.com.
Chinedu P AnokwuruChemistry Department, School of Mathematical and Natural Sciences, University of Venda, Private Bag X5050, 0950 Thohoyandou, South Africa. anokwuruchi@gmail.com.
Muendi T SigidiMicrobiology Department, School of Mathematical and Natural Sciences, University of Venda, Private Bag X5050, 0950 Thohoyandou, South Africa. muendi.sigidi@yahoo.com.
Milingoni P TshisikhaweBotany Department, School of Mathematical and Natural Sciences, University of Venda, Private Bag X5050, 0950 Thohoyandou, South Africa. peter.tshisikhawe@univen.ac.za.
Isaiah I D RamaiteChemistry Department, School of Mathematical and Natural Sciences, University of Venda, Private Bag X5050, 0950 Thohoyandou, South Africa. isaiah.ramaite@univen.ac.za.
Afsatou N TraoréMicrobiology Department, School of Mathematical and Natural Sciences, University of Venda, Private Bag X5050, 0950 Thohoyandou, South Africa. afsatou.traore@univen.ac.za.
Heinrich HoppeDepartment of Biochemistry and Microbiology, Rhodes University, P.O. Box 94, Grahamstown 6140, South Africa. h.hoppe@ru.ac.za.
Addmore ShonhaiBiochemistry Department, School of Mathematical and Natural Sciences, University of Venda, Private Bag X5050, 0950 Thohoyandou, South Africa. addmore.shonhai@univen.ac.za.
Natasha PotgieterMicrobiology Department, School of Mathematical and Natural Sciences, University of Venda, Private Bag X5050, 0950 Thohoyandou, South Africa. natasha.potgieter@univen.ac.za.
University of Venda · ZARhodes University · ZA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Malaria parasites are increasingly becoming resistant to currently used antimalarial therapies, therefore there is an urgent need to expand the arsenal of alternative antimalarial drugs. In addition, it is also important to identify novel antimalarial drug targets. In the current study, extracts of two plants,

Indexed as

Adenosine TriphosphatasesAntimalarialsDose-Response Relationship, DrugHSP70 Heat-Shock ProteinsPhenolsPlant ExtractsPlasmodiumPlasmodium falciparumProtein BindingProtein StabilityPterocarpusZiziphusAdenosine TriphosphatasesAntimalarialsHSP70 Heat-Shock ProteinsPhenolsPlant Extractsantimalarial activityHsp70molecular chaperonePterocarpus angolensisZiziphus mucronata

Identifiers

PMID28788073
PMCPMC6152082
OpenAlexW2740180685

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.