Evidence map›Paper›PMID 28788072›Full record

ArticleToxins2017

The Middle Fragment of Helicobacter pylori CagA Induces Actin Rearrangement and Triggers Its Own Uptake into Gastric Epithelial Cells.

Abolghasem Tohidpour, Rebecca J Gorrell, Anna Roujeinikova, Terry Kwok

Open access · goldAbstract read
In one paragraph

Article in Toxins, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 18 citations in OpenAlex.

  1. Antibiotics Impact the Cytotoxicity and Cytopathic Effect ofInternational journal of molecular sciences · 2025
    Article
  2. Biphasic Adaptations of Gastric Epithelial Cells in ChronicInternational journal of molecular sciences · 2025
    Article
  3. Frontiers in cell and developmental biology · 2025
    Article
  4. Article
  5. Article
  6. Influence of the Microbiome Metagenomics and Epigenomics on Gastric Cancer.International journal of molecular sciences · 2022
    Review
  7. Article
  8. Review
  9. Article
  10. Review
  11. Article
  12. Frontiers in cell and developmental biology · 2020
    Article
  13. Special Issue "Toxins · 2018
    Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Abolghasem TohidpourInfection and Immunity Program, Monash Biomedicine Discovery Institute, Department of Microbiology, Monash University, Clayton, Victoria 3800, Australia. a.tohidpour@gmail.com.
Rebecca J GorrellInfection and Immunity Program, Monash Biomedicine Discovery Institute, Department of Microbiology, Monash University, Clayton, Victoria 3800, Australia. rebecca.gorrell@monash.edu.
Anna RoujeinikovaInfection and Immunity Program, Monash Biomedicine Discovery Institute, Department of Microbiology, Monash University, Clayton, Victoria 3800, Australia. anna.roujeinikova@monash.edu.
Terry KwokInfection and Immunity Program, Monash Biomedicine Discovery Institute, Department of Microbiology, Monash University, Clayton, Victoria 3800, Australia. terry.kwok@monash.edu.
Australian Regenerative Medicine Institute · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cytotoxin-associated gene product A (CagA) is a major virulence factor secreted by

Indexed as

Host-Pathogen InteractionsActinsAntigens, BacterialBacterial ProteinsCells, CulturedEndocytosisEpithelial CellsGastric MucosaHelicobacter pyloriHumansImmobilized ProteinsRecombinant ProteinsActinsAntigens, BacterialBacterial ProteinscagA protein, Helicobacter pyloriImmobilized ProteinsRecombinant Proteinsactin polymerizationendocytosisintegrinmacrospike protrusionsphosphatidylserine

Identifiers

PMID28788072
PMCPMC5577571
OpenAlexW2739840427

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.