Evidence map›Paper›PMID 28788060›Full record

ReviewNutrients2017

Myth or Reality-Transdermal Magnesium?

Uwe Gröber, Tanja Werner, Jürgen Vormann, Klaus Kisters

Open access · goldAbstract readReview
In one paragraph

Review in Nutrients, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 28 citations in OpenAlex.

  1. Observational
  2. Review
  3. Article
  4. Article
  5. 'Magnesium'-the master cation-as a drug-possibilities and evidences.Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2021
    Review
  6. Article
  7. Review
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Uwe GröberAkademie für Mikronährstoffmedizin, Zweigertstr. 55, 45130 Essen, Germany. uwegroeber@gmx.net.
Tanja WernerIPEV Institute for Prevention and Nutrition, Adalperostr. 37, D-85737 Ismaning, Germany. werner.tanja@protina.de.
Jürgen VormannIPEV Institute for Prevention and Nutrition, Adalperostr. 37, D-85737 Ismaning, Germany. vormann@ipev.de.
Klaus KistersAkademie für Mikronährstoffmedizin, Zweigertstr. 55, 45130 Essen, Germany. kisters@annahospital.de.
St. Anna Hospital · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In the following review, we evaluated the current literature and evidence-based data on transdermal magnesium application and show that the propagation of transdermal magnesium is scientifically unsupported. The importance of magnesium and the positive effects of magnesium supplementation are extensively documented in magnesium deficiency, e.g., cardiovascular disease and diabetes mellitus. The effectiveness of oral magnesium supplementation for the treatment of magnesium deficiency has been studied in detail. However, the proven and well-documented oral magnesium supplementation has become questioned in the recent years through intensive marketing for its transdermal application (e.g., magnesium-containing sprays, magnesium flakes, and magnesium salt baths). In both, specialist and lay press as well as on the internet, there are increasing numbers of articles claiming the effectiveness and superiority of transdermal magnesium over an oral application. It is claimed that the transdermal absorption of magnesium in comparison to oral application is more effective due to better absorption and fewer side effects as it bypasses the gastrointestinal tract.

Indexed as

Administration, CutaneousAdministration, OralBiological TransportHumansMagnesiumMagnesium DeficiencyMagnesiummagnesiumtransdermal

Identifiers

PMID28788060
PMCPMC5579607
OpenAlexW2739984677

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.