Evidence map›Paper›PMID 28788056›Full record

ArticleInternational journal of molecular sciences2017

Immuno-Modulatory and Anti-Inflammatory Effects of Dihydrogracilin A, a Terpene Derived from the Marine Sponge Dendrilla membranosa.

Elena Ciaglia, Anna Maria Malfitano, Chiara Laezza, Angelo Fontana, Genoveffa Nuzzo, Adele Cutignano, Mario Abate, Marco Pelin, Silvio Sosa, Maurizio Bifulco and 1 more

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
8.4field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 59 citations in OpenAlex.

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  15. Pharmaceuticals (Basel, Switzerland) · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 1 country.

Elena CiagliaDepartment of Medicine, Surgery and Dentistry "Scuola Medica Salernitana", University of Salerno, Via Salvatore Allende, 84081 Baronissi Salerno, Italy. eciaglia@unisa.it.
Anna Maria MalfitanoDepartment of Pharmacy, University of Salerno, Via Giovanni Paolo II, 84084 Fisciano, Salerno, Italy. amalfitano@unisa.it.
Chiara LaezzaDepartment of Biology and Cellular and Molecular Pathology, University of Naples Federico II, Via Pansini, 80131 Naples, Italy. chiara.laezza@cnr.it.
Angelo FontanaBio-Organic Chemistry Unit, Institute of Biomolecular Chemistry-CNR, Via Campi Flegrei 34, Pozzuoli, 80131 Naples; Italy, afontana@icb.cnr.it (A.F.). afontana@icb.cnr.it.
Genoveffa NuzzoBio-Organic Chemistry Unit, Institute of Biomolecular Chemistry-CNR, Via Campi Flegrei 34, Pozzuoli, 80131 Naples; Italy, afontana@icb.cnr.it (A.F.). nuzzo.genoveffa@icb.cnr.it.
Adele CutignanoBio-Organic Chemistry Unit, Institute of Biomolecular Chemistry-CNR, Via Campi Flegrei 34, Pozzuoli, 80131 Naples; Italy, afontana@icb.cnr.it (A.F.). acutignano@icb.cnr.it.
Mario AbateDepartment of Medicine, Surgery and Dentistry "Scuola Medica Salernitana", University of Salerno, Via Salvatore Allende, 84081 Baronissi Salerno, Italy. m.abate23@studenti.unisa.it.
Marco PelinDepartment of Life Sciences, University of Trieste, 34127 Trieste, Italy. mpelin@units.it.
Silvio SosaDepartment of Life Sciences, University of Trieste, 34127 Trieste, Italy. ssosa@units.it.
Maurizio BifulcoDepartment of Medicine, Surgery and Dentistry "Scuola Medica Salernitana", University of Salerno, Via Salvatore Allende, 84081 Baronissi Salerno, Italy. mbifulco@unisa.it.
Patrizia GazzerroDepartment of Pharmacy, University of Salerno, Via Giovanni Paolo II, 84084 Fisciano, Salerno, Italy. pgazzerro@unisa.it.
University of Salerno · ITInstitute of Polymers, Composites and Biomaterials · ITUniversity of Trieste · ITInstitute for Experimental Endocrinology and Oncology · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We assessed the immunomodulatory and anti-inflammatory effects of 9,11-dihydrogracilin A (DHG), a molecule derived from the Antarctic marine sponge

Indexed as

AnimalsAnti-Inflammatory AgentsAquatic OrganismsBiological ProductsCell MovementCell ProliferationCell SurvivalCytokinesHumansImmunologic FactorsImmunomodulationKeratinocytesKiller Cells, NaturalLeukocytes, MononuclearPoriferaSignal TransductionAnti-Inflammatory AgentsBiological ProductsCytokinesImmunologic FactorsTerpenesinflammationlymphocytesmarine spongenatural compound

Identifiers

PMID28788056
PMCPMC5578033
OpenAlexW2741365669

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.