ArticleMaterials (Basel, Switzerland)2015
Modification of pH Conferring Virucidal Activity on Dental Alginates.
Article in Materials (Basel, Switzerland), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
5 citing papers in PubMed.
- State of Innovation in Alginate-Based Materials.Marine drugs · 2023Review
- Review
- Effect of a Topical Formulation on Infective Viral Load in Lambs Naturally Infected with Orf Virus.Veterinary medicine (Auckland, N.Z.) · 2021Article
- COVID-19 and a novel initiative to improve safety by 3D printing personal protective equipment parts from computed tomography.3D printing in medicine · 2020Article
- Alginate Materials and Dental Impression Technique: A Current State of the Art and Application to Dental Practice.Marine drugs · 2018Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
To formulate an alginate dental impression material with virucidal properties, experimental alginate dental impression materials were developed and the formulations adjusted in order to study the effect on pH profiles during setting. Commercially available materials served as a comparison. Eight experimental materials were tested for antiviral activity against Herpes Simplex Virus type 1 (HSV-1). Changing the amount of magnesium oxide (MgO) used in the experimental formulations had a marked effect on pH. Increasing MgO concentration corresponded with increased pH values. All experimental materials brought about viral log reductions ranging between 0.5 and 4.0 over a period of 4 h. The material with the lowest pH was the most effective. The current work highlights the very important role of MgO in controlling pH profiles. This knowledge has been applied to the formulation of experimental alginates; where materials with pH values of approximately 4.2-4.4 are able to achieve a significant log reduction when assayed against HSV-1.
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