Evidence map›Paper›PMID 28787738›Full record

Trial reportObesity facts2017

A Structured, Manual-Based Low-Level Intervention vs. Treatment as Usual Evaluated in a Randomized Controlled Trial for Adolescents with Extreme Obesity - the STEREO Trial.

Yvonne Mühlig, André Scherag, Annika Bickenbach, Ulrike Giesen, Reinhard Holl, Rolf Holle, Wieland Kiess, Belinda Lennerz, Diana Lütke Brintrup, Anja Moss and 8 more

Open access · goldAbstract readComparative StudyRandomized Controlled Trial
In one paragraph

Trial report in Obesity facts, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 8 citations in OpenAlex.

  1. Trial
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 9 institutions in 4 countries.

Yvonne MühligDepartment of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, University Hospital Essen, University of Duisburg-Essen, Essen, Germany.
André Scherag
Annika Bickenbach
Ulrike Giesen
Reinhard Holl
Rolf Holle
Wieland Kiess
Belinda Lennerz
Diana Lütke Brintrup
Anja Moss
Madlen Neef
Claudia Ose
Thomas Reinehr
Christina M Teuner
Susanna Wiegand
Barbara Wolters
Martin Wabitsch
Johannes Hebebrand
Essen University Hospital · DEUniversität Ulm · DECenter for Environmental Health · USCharité - Universitätsmedizin Berlin · DELeipzig University of Applied Sciences · DEWitten/Herdecke University · DEJena University Hospital · DEUniversity of Duisburg-Essen · DEZimmer Biomet (Netherlands) · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTo compare efficacy and safety of a manual-based low-level psychological intervention with treatment as usual (weight loss treatment).

methodsA two-armed randomized controlled trial without blinding and computer-based stratified block randomization included adolescents and young adults (14.0-24.9 years) with a BMI ≥ 30 kg/m2 at five German university hospitals. Primary outcomes were adherence (participation rate ≥ 5/6 sessions) and quality of life (DISABKIDS-37) 6 months after randomization. Secondary outcomes included depression, self-esteem, and perceived stress scores.

resultsOf 397 screened adolescents, 119 (mean BMI 40.4 ± 7.0 kg/m2, 49.6% female) were randomized to the manual-based low-level intervention (n = 59) or treatment as usual (n = 60). We observed no group difference for adherence (absolute risk reduction 0.4%, 95% CI -14.7% to 15.5%; p = 1.0) or health-related quality of life (score difference 8.1, 95% CI -2.1 to 18.3; p = 0.11). Among all secondary outcomes, we detected explorative evidence for an effect on the DISABKIDS-37 'social exclusion' subscale (score difference 15.5; 95% CI 1.6-29.4; p = 0.03). 18/19 adverse events occurred in 26 participants, none were classified as serious.

conclusionAdherence to a coping-oriented intervention was comparable to weight loss treatment, although it was weak in both interventions. Psychological interventions may help to overcome social isolation; further confirmation is required.

Indexed as

Adaptation, PsychologicalAdolescentAdultBody Mass IndexDepressionFemaleHumansMaleObesityObesity, MorbidQuality of LifeSelf ConceptSocial IsolationWeight LossYoung AdultAdherenceAdolescentsExtreme obesityHRQoLQuality of lifeYouth

Identifiers

PMID28787738
PMCPMC5644941
OpenAlexW2743125456

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.