Evidence map›Paper›PMID 28787670›Full record

ArticleInternational journal of surgery case reports2017

Surgical approach in thymectomy: Our experience and review of the literature.

Vincenzo Giuseppe Di Crescenzo, Filomena Napolitano, Claudio Panico, Rosa Maria Di Crescenzo, Pio Zeppa, Alessandro Vatrella, Paolo Laperuta

Open access · goldAbstract read
In one paragraph

Article in International journal of surgery case reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 35 citations in OpenAlex.

  1. Complications of robot-assisted thymectomy: A single-arm meta-analysis and systematic review.The international journal of medical robotics + computer assisted surgery : MRCAS · 2021
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  16. A case of thymoma in myasthenia gravis: Successful outcome after thymectomy.International journal of surgery case reports · 2019
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Vincenzo Giuseppe Di CrescenzoDepartment of Medicine and Surgery, Thoracic Surgery Unit, University of Salerno, Italy. Electronic address: vdicrescenzo@unisa.it.
Filomena NapolitanoDepartment of Medicine and Surgery, Thoracic Surgery Unit, University of Salerno, Italy. Electronic address: milena.napolitano@yahoo.it.
Claudio PanicoDepartment of Medicine and Surgery, Thoracic Surgery Unit, University of Salerno, Italy. Electronic address: panico@sangiovannieruggi.it.
Rosa Maria Di CrescenzoDepartment of Medicine and Surgery, Pathology Unit, Federico II University of Naples, Italy. Electronic address: rose.dicrescenzo@libero.it.
Pio ZeppaDepartment of Medicine and Surgery, Pathology Unit, University of Salerno, Italy. Electronic address: pzeppa@unisa.it.
Alessandro VatrellaDepartment of Medicine and Surgery, Section of Respiratory Diseases, University of Salerno, Salerno, Italy. Electronic address: avatrella@unisa.it.
Paolo LaperutaDepartment of Medicine and Surgery, Thoracic Surgery Unit, University of Salerno, Italy. Electronic address: laper@libero.it.
University of Salerno · ITOspedali Riuniti San Giovanni di Dio e Ruggi d'Aragona · ITUniversity of Naples Federico II · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimThymectomy is the main treatment for thymoma and patients with myasthenia gravis (MG). The traditional approach is through a median sternotomy, but, recently, thymectomy through minimally invasive approaches is increasingly performed. Our purpose is an analysis and discussion of the clinical presentation, the diagnostic procedures and the surgical technique. We also consider post-operative complications and results, over a period of 5 years (May 2011-June 2016), in thymic masses admitted in our Thoracic Surgery Unit.

methodsWe analyzed 8 patients who underwent surgical treatment for thymic masses over a period of 5 years. 6 patients (75%) had thymoma, 2 patients (25%) had thymic carcinomas. 2 patients with thymoma (33%) had myasthenia gravis. We performed a complete surgical resection with median sternotomy as standard approach.

resultsOne patient (12%) died in the postoperative period. The histological study revealed 6 (75%) thymoma and 2 (25%) thymic carcinomas. Post-operative morbidity occurred in 2 patients (25%) and were: pneumonia in 1 case (12%), atrial fibrillation and pleural effusion in 2 patients (25%). One patient with thymoma type A recurred at skeletal muscle 2-years after surgery.

conclusionsThymic malignancies are rare tumors. Surgical resection is the main treatment, but a multimodal approach is useful for many patients. Radical thymectomy is completed removing all the soft tissue in the anterior mediastinum between the two phrenic nerves and this is the most important factor in controlling myasthenia and influencing survival in patients with thymoma. Open (median sternotomy) approach has been the standard approach for thymectomy for the better visualization of the anatomical structures. Actually, video-assisted thoracoscopic surgery (VATS) thymectomy and robotic video-assisted thoracoscopic (R-VATS) approach versus open surgery has an equal if not superior oncological efficacy, better perioperative complications and survival outcomes.

Indexed as

Median sternotomyMyasthenia gravisRobotic video-assisted thoracoscopic (R-VATS)ThymectomyThymomaVideo-assisted thoracoscopic surgery (VATS)

Identifiers

PMID28787670
PMCPMC5545819
OpenAlexW2737573242

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.