Evidence map›Paper›PMID 28787093›Full record

ArticleGlia2017

The α2β2 isoform combination dominates the astrocytic Na

Anca Stoica, Brian Roland Larsen, Mette Assentoft, Rikke Holm, Leanne Melissa Holt, Frederik Vilhardt, Bente Vilsen, Karin Lykke-Hartmann, Michelle Lynne Olsen, Nanna MacAulay

Open access · greenAbstract read
In one paragraph

Article in Glia, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
5.1field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 59 citations in OpenAlex.

  1. Article
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  14. Article
  15. Molecular mechanisms of brain water transport.Nature reviews. Neuroscience · 2021
    Review
  16. Activation and Role of Astrocytes in Ischemic Stroke.Frontiers in cellular neuroscience · 2021
    Review
  17. Article
  18. Article
  19. Article
  20. NaJournal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Anca StoicaCenter for Neuroscience, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.ORCID 0000-0003-3403-2783
Brian Roland LarsenCenter for Neuroscience, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.ORCID 0000-0003-2654-6645
Mette AssentoftCenter for Neuroscience, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Rikke HolmDepartment of Biomedicine, Aarhus University, Aarhus, Denmark.
Leanne Melissa HoltDepartment of Cell, Developmental, and Integrative Biology, University of Alabama at Birmingham, Birmingham, Alabama.
Frederik VilhardtDepartment of Cellular and Molecular Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Bente VilsenDepartment of Biomedicine, Aarhus University, Aarhus, Denmark.
Karin Lykke-HartmannDepartment of Biomedicine, Aarhus University, Aarhus, Denmark.
Michelle Lynne OlsenDepartment of Cell, Developmental, and Integrative Biology, University of Alabama at Birmingham, Birmingham, Alabama.
Nanna MacAulayCenter for Neuroscience, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
University of Copenhagen · DKAarhus University · DKUniversity of Alabama at Birmingham · US

Funding

Epigenetic Regulation of Kir4.1 and GLT1 in PathophysiologyR01NS075062 · NINDS · VIRGINIA POLYTECHNIC INST AND ST UNIV · PI OLSEN, MICHELLE L · 2013 to 2017
$1.6M
Astrocytes are a primary target of neuronal-derived BDNF: a novel mechanism for dysfunction in Rett SyndromeF31NS100259 · NINDS · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI HOLT, LEANNE · 2017 to 2019
$134k
NINDS NIH HHS F31 NS100259NINDS NIH HHS R01 NS075062
6 · The paper itself

Abstract

Synaptic activity results in transient elevations in extracellular K

Indexed as

Adenosine TriphosphatasesAnimalsAnimals, NewbornArginineAstrocytesCation Transport ProteinsCD11b AntigenCell Adhesion Molecules, NeuronalCells, CulturedExcitatory Amino AcidsFemaleGlycineMaleMiceMice, Inbred C57BLMice, TransgenicAdenosine TriphosphatasesArginineAtp1a2 protein, mouseAtp1b2 protein, mouseCation Transport ProteinsCD11b AntigenCell Adhesion Molecules, NeuronalExcitatory Amino AcidsGlycineProtein IsoformsSodium-Potassium-Exchanging ATPaseastrocytesexpression patternisoform-pairingisoformsK+ clearance

Identifiers

PMID28787093
PMCPMC12247536
OpenAlexW2742893892

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.