Evidence map›Paper›PMID 28786958›Full record

ArticleToxins2017

Spider Neurotoxins, Short Linear Cationic Peptides and Venom Protein Classification Improved by an Automated Competition between Exhaustive Profile HMM Classifiers.

Dominique Koua, Lucia Kuhn-Nentwig

Abstract read
In one paragraph

Article in Toxins, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Quantitative analysis of growth and diversification in venom data using database metrics.Database : the journal of biological databases and curation · 2026
    Article
  2. A large language model for predicting neurotoxic peptides and neurotoxins.Protein science : a publication of the Protein Society · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Dominique KouaDepartement Agriculture et Ressources Animals, Institut National Polytechnique Félix Houphouet-Boigny, BP 1093 Yamoussoukro, Ivory Coast. dominique.koua@iee.unibe.ch.
Lucia Kuhn-NentwigInstitute of Ecology and Evolution, University of Bern, Baltzerstrasse 6, 3012 Bern, Switzerland. lucia.kuhn@iee.unibe.ch.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Spider venoms are rich cocktails of bioactive peptides, proteins, and enzymes that are being intensively investigated over the years. In order to provide a better comprehension of that richness, we propose a three-level family classification system for spider venom components. This classification is supported by an exhaustive set of 219 new profile hidden Markov models (HMMs) able to attribute a given peptide to its precise peptide type, family, and group. The proposed classification has the advantages of being totally independent from variable spider taxonomic names and can easily evolve. In addition to the new classifiers, we introduce and demonstrate the efficiency of

Indexed as

AnimalsArthropod ProteinsDatabases, ProteinNeurotoxinsPeptidesProteomicsSpidersSpider VenomsArthropod ProteinsNeurotoxinsPeptidesSpider Venomsclassificationhmmcompetemachine learningprofile HMMspidertoxin

Identifiers

PMID28786958
PMCPMC5577579

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.