Evidence map›Paper›PMID 28786338›Full record

ArticleJournal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism2019

Collateral perfusion using arterial spin labeling in symptomatic versus asymptomatic middle cerebral artery stenosis.

Xin Lou, Xiaoxiao Ma, David S Liebeskind, Ning Ma, Chenglin Tian, Jinhao Lyu, Xiaojing Long, Lin Ma, Danny Jj Wang

Abstract read
In one paragraph

Article in Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Xin Lou1 Department of Radiology and Department of Neurology, Chinese People's Liberation Army (PLA), General Hospital, Beijing, China.
Xiaoxiao Ma1 Department of Radiology and Department of Neurology, Chinese People's Liberation Army (PLA), General Hospital, Beijing, China.
David S Liebeskind2 Department of Neurology, University of California Los Angeles, Los Angeles, CA, USA.
Ning Ma3 Department of Interventional Neuroradiology, Beijing Tiantan Hospital, Capital Medical University, China National Clinical Research Center for NeurologicalDiseases, Center of Stroke, Beijing Institute for Brain Disorders, Beijing, China.
Chenglin Tian1 Department of Radiology and Department of Neurology, Chinese People's Liberation Army (PLA), General Hospital, Beijing, China.
Jinhao Lyu1 Department of Radiology and Department of Neurology, Chinese People's Liberation Army (PLA), General Hospital, Beijing, China.
Xiaojing Long4 Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, China.
Lin Ma1 Department of Radiology and Department of Neurology, Chinese People's Liberation Army (PLA), General Hospital, Beijing, China.
Danny Jj Wang5 Laboratory of FMRI Technology (LOFT), Mark & Mary Stevens Neuroimaging and Informatics Institute, Keck School of Medicine, University of Southern California, CA, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The purpose was to assess the difference of collaterals in symptomatic versus asymptomatic patients with unilateral middle cerebral artery (MCA) stenosis by comparing cerebral blood flow (CBF) at two post labeling delays (PLD) using three-dimensional pseudo-continuous arterial spin labeling (3D pCASL). Eighty-one patients (49 symptomatic and 32 asymptomatic) with unilateral MCA stenosis ≥50% who underwent pCASL with two PLDs were included. Mean CBF and CBF subtraction images between two PLDs of MCA territories were compared in symptomatic and asymptomatic groups, respectively. Compared with the asymptomatic group, patients with symptomatic MCA stenosis had significantly lower CBF in the MCA territory of stenotic side at each PLD. The CBF of stenotic territory showed greater increase than that of normal side from PLD 1.5 to 2.5 s. The CBF of asymptomatic MCA territory increased similarly with that of symptomatic MCA territory from PLD of 1.5 to 2.5 s in stenotic side, while symptomatic patients experienced significantly slower antegrade flow. On CBF subtraction images, asymptomatic patients showed larger volume of differences between PLD of 1.5 and 2.5 s compared with those of symptomatic patients ( p = 0.037). The results suggest that more robust collateral perfusion on two-delay 3D pCASL is present in asymptomatic patients compared with symptomatic patients.

Indexed as

Collateral CirculationAgedAngiography, Digital SubtractionCerebrovascular CirculationConstriction, PathologicFemaleHumansMagnetic Resonance ImagingMaleMiddle AgedMiddle Cerebral ArteryNeuroimagingProspective StudiesSpin LabelsSpin LabelsArterial spin labelingcollateral circulationischemic strokeperfusionpost labeling delay

Identifiers

PMID28786338
PMCPMC6311674

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.