Evidence map›Paper›PMID 28786062›Full record

ArticleJournal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban2017

Hypoxia enhances the therapeutic potential of superparamagnetic iron oxide-labeled adipose-derived stem cells for myocardial infarction.

Jian Wang, Bo Xiang, Ji-Xian Deng, Hung-Yu Lin, Darren H Freed, Rakesh C Arora, Gang-Hong Tian

Abstract read
PubMed Publisher
In one paragraph

Article in Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. IntegrinInternational journal of stem cells · 2024
    Article
  4. Article
  5. Overexpression of integrin βAnnals of translational medicine · 2022
    Article
  6. CXCR4Stem cells international · 2022
    Article
  7. Review
  8. Review
  9. Article
  10. Review
  11. Article
  12. Review
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Jian WangDepartment of Vascular Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China. jianwang1030@126.com.
Bo XiangNational Research Council of Canada, Winnipeg, R3B 1Y6, Canada.
Ji-Xian DengNational Research Council of Canada, Winnipeg, R3B 1Y6, Canada.
Hung-Yu LinNational Research Council of Canada, Winnipeg, R3B 1Y6, Canada.
Darren H FreedNational Research Council of Canada, Winnipeg, R3B 1Y6, Canada.
Rakesh C AroraNational Research Council of Canada, Winnipeg, R3B 1Y6, Canada.
Gang-Hong TianNational Research Council of Canada, Winnipeg, R3B 1Y6, Canada. Ganghong.Tian@nrc-cnrc.gc.ca.
University of Manitoba · CANational Research Council Canada · CAHuazhong University of Science and Technology · CNNational Research Council Institute for Biodiagnostics · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Adipose-derived stem cells (ASCs) induce therapeutic angiogenesis due to pro-angiogenic cytokines secretion. Superparamagnetic iron oxide (SPIO) nanoparticles are critical for magnetic resonance (MR) tracking of implanted cells. Hypoxia is a powerful stimulus for angiogenic activity of ASCs. In this study, we investigated whether therapeutic potency could be enhanced by implantation of hypoxia-preconditioned SPIO-labeled ASCs (

Indexed as

Stem Cell TransplantationAdipose TissueAnimalsCapillariesCell HypoxiaCells, CulturedHypoxia-Inducible Factor 1, alpha SubunitMagnetite NanoparticlesMaleMyocardial ContractionMyocardial InfarctionMyocardiumRats, Inbred LewRNA, MessengerStem CellsVascular Endothelial Growth Factor AHypoxia-Inducible Factor 1, alpha SubunitMagnetite NanoparticlesRNA, MessengerVascular Endothelial Growth Factor Aadipose-derived stem cellshypoxiamyocardial infarctionsuperparamagnetic iron oxide

Identifiers

PMID28786062
OpenAlexW2756989904

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.