Evidence map›Paper›PMID 28786032›Full record

ArticleCellular and molecular neurobiology2018

Haloperidol Affects Plasticity of Differentiated NG-108 Cells Through σ1R/IP

Jana Kubickova, Lubomira Lencesova, Lucia Csaderova, Tibor Stracina, Sona Hudecova, Petr Babula, Eva Rozborilova, Marie Novakova, Olga Krizanova

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cellular and molecular neurobiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 13 citations in OpenAlex.

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  7. Partners in Crime: Towards New Ways of Targeting Calcium Channels.International journal of molecular sciences · 2019
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Jana KubickovaInstitute of Clinical and Translational Research, Biomedical Research Center, Slovak Academy of Sciences, Dubravska cesta 9, 84505, Bratislava, Slovakia.
Lubomira LencesovaInstitute of Clinical and Translational Research, Biomedical Research Center, Slovak Academy of Sciences, Dubravska cesta 9, 84505, Bratislava, Slovakia.
Lucia CsaderovaInstitute of Virology, Biomedical Research Center, Slovak Academy of Sciences, Bratislava, Slovakia.
Tibor StracinaDepartment of Physiology, Faculty of Medicine, Masaryk University, Brno, Czech Republic.
Sona HudecovaInstitute of Clinical and Translational Research, Biomedical Research Center, Slovak Academy of Sciences, Dubravska cesta 9, 84505, Bratislava, Slovakia.
Petr BabulaDepartment of Physiology, Faculty of Medicine, Masaryk University, Brno, Czech Republic.
Eva RozborilovaClinics of Pneumology and Phthisiology, Jessenius Faculty of Medicine, Martin, Slovakia.
Marie NovakovaDepartment of Physiology, Faculty of Medicine, Masaryk University, Brno, Czech Republic.
Olga KrizanovaInstitute of Clinical and Translational Research, Biomedical Research Center, Slovak Academy of Sciences, Dubravska cesta 9, 84505, Bratislava, Slovakia. olga.krizanova@savba.sk.
Masaryk University · CZBiomedical Research Center of the Slovak Academy of Sciences · SKComenius University Bratislava · SKInstitute of Virology of the Slovak Academy of Sciences · SK

Funding

Agentúra na Podporu Výskumu a Vývoja APVV 51-0045-11Masaryk University grant MUNI/A/1326/2014Vedecká Grantová Agentúra MŠVVaŠ SR a SAV VEGA 2/0082/16
6 · The paper itself

Abstract

Haloperidol is an antipsychotic agent that primarily acts as an antagonist of D2 dopamine receptors. Besides other receptor systems, it targets sigma 1 receptors (σ1Rs) and inositol 1,4,5-trisphosphate receptors (IP

Indexed as

AnimalsAntipsychotic AgentsCell DifferentiationCell Line, TumorDose-Response Relationship, DrugHaloperidolInositol 1,4,5-Trisphosphate ReceptorsMiceNeuronal PlasticityProtein BindingRatsReceptors, sigmaSigma-1 ReceptorAntipsychotic AgentsHaloperidolInositol 1,4,5-Trisphosphate ReceptorsItpr1 protein, ratReceptors, sigmaSigma-1 ReceptorBD 1047Dopamine 2 receptorHaloperidolInositol 1,4,5-trisphosphate receptorNG-108 cellsSigma 1 receptor

Identifiers

PMID28786032
PMCPMC5775985
OpenAlexW2742612100

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.