ArticleEuropean radiology2018
Safety analysis of holmium-166 microsphere scout dose imaging during radioembolisation work-up: A cohort study.
Article in European radiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
31 citing papers in PubMed, 1 synthesis or guideline pooled it.
- EANM procedure guideline for the treatment of liver cancer and liver metastases with intra-arterial radioactive compounds.European journal of nuclear medicine and molecular imaging · 2022Guideline
- Safety and Efficacy ofJournal of nuclear medicine : official publication, Society of Nuclear Medicine · 2022Trial
- Dynamic contrast-enhanced ultrasound predicts microsphere biodistribution in real-time during transarterial radioembolization.Communications medicine · 2026Article
- Assessment and clinical relevance of pulmonary shunt onEJNMMI physics · 2025Article
- Towards harmonized holmium-166 SPECT image quality for dosimetry: a multi-center, multi-vendor study.EJNMMI physics · 2025Article
- Angiographic Aspects of Transarterial Radioembolization: A Comparison of Technical Options to Avoid Extrahepatic Microsphere Depositions.Biomedicines · 2024Article
- Gamma camera imaging characteristics ofEJNMMI physics · 2024Article
- Intraprocedural C-arm dual-phase cone-beam enhancement patterns correlate with tumor absorbed dose after radioembolization.Medical physics · 2024Article
- Lung Mean Dose Prediction in Transarterial Radioembolization (TARE): Superiority of [Cardiovascular and interventional radiology · 2024Article
- Safety and efficacy of Holmium-166 selective internal radiotherapy of primary and secondary liver cancer confirmed by real-world data.Frontiers in oncology · 2024Article
- Transarterial Radioembolization: Overview of Radioembolic Devices.Seminars in interventional radiology · 2023Review
- Dose finding study for unilobar radioembolization using holmium-166 microspheres to improve resectability in patients with HCC: the RALLY protocol.BMC cancer · 2023Article
- Article
- Selective internal radiotherapy in Germany: a review of indications and hospital mortality from 2012 to 2019.Journal of clinical and translational research · 2023Article
- A Theranostic Approach in SIRT: Value of Pre-Therapy Imaging in Treatment Planning.Journal of clinical medicine · 2022Review
- Role of Transhepatic Arterial Radioembolization in Metastatic Colorectal Cancer.Cardiovascular and interventional radiology · 2022Review
- Trans-arterial Radioembolization Dosimetry in 2022.Cardiovascular and interventional radiology · 2022Review
- Holmium-166 Radioembolization: Current Status and Future Prospective.Cardiovascular and interventional radiology · 2022Review
- SIRT in 2025.Cardiovascular and interventional radiology · 2022Review
- Article
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
objectiveRadioembolisation is generally preceded by a scout dose of technetium-99m-macroaggregated albumin to estimate extrahepatic shunting of activity. Holmium-166 microspheres can be used as a scout dose (±250 MBq) and as a therapeutic dose. The general toxicity of a holmium-166 scout dose (
methodsAll patients who received a
resultsIn total, 82 patients were included. No relevant clinical toxicity occurred. Six patients had an extrahepatic deposition of
conclusionThese results support the safety of 250 MBq KEY POINTS: • A holmium-166 scout dose is safe in a clinical setting. • Holmium-166 scout dose is a safe alternative for
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Registered trials
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