Evidence map›Paper›PMID 28785969›Full record

ReviewCurrent heart failure reports2017

Acute Heart Failure: Definition, Classification and Epidemiology.

Sameer Kurmani, Iain Squire

2 registry-linked trialsAbstract readReview
In one paragraph

Review in Current heart failure reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 163 papers, 13 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
163citing papers in PubMed, 13 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05204238 unknown statusnot on this mapstarted 2020, after this paper: background citation

Follow Up of acuTe Heart failUre: a pRospective Echocardiographic and Clinical Study (FUTURE)

TypeobservationalSponsorUniversity of SienaRan2020 to 2022Enrolled998ConditionsHeart Failure, Heart Failure With Preserved Ejection Fraction, Heart Failure With Mid Range Ejection Fraction, Heart Failure With Reduced Ejection FractionArmsTransthoracic Echocardiography
NCT06414759 phase4unknown statusnot on this mapstarted 2024, after this paper: background citation

Efficacy and Safety of Combination Diuretic Therapy in Patients With Acute Decompensated Heart Failure and Volume Overload

TypeinterventionalSponsorCairo UniversityRan2024 to 2025Enrolled110ConditionsAcute Decompensated Heart Failure, Volume Overload, EdemaArmsAcetazolamide, Metolazone, IV Loop Diuretics
3 · Its place in the literature

Who cites it

163 citing papers in PubMed, 13 syntheses or guidelines pooled it.

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  9. The prognostic significance of bundle branch block in acute heart failure: a systematic review and meta-analysis.Clinical research in cardiology : official journal of the German Cardiac Society · 2023
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  11. Vascular mechanisms in acute unilateral peripheral vestibulopathy: a systematic review.Acta otorhinolaryngologica Italica : organo ufficiale della Societa italiana di otorinolaringologia e chirurgia cervico-facciale · 2021
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103 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Sameer KurmaniDepartment of Cardiovascular Sciences, University of Leicester Glenfield Hospital, Leicester, LE3 9QP, UK. sak36@le.ac.uk.
Iain SquireNIHR Leicester Biomedical Research Centre, Glenfield Hospital, Leicester, LE3 9QP, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purpose of reviewThe purpose of this review is to describe the extent and scope of acute heart failure (AHF), place it within its clinical context and highlight some of the difficulties in defining it as a pathophysiological entity. RECENT

findingsA diagnosis of AHF is made when patients present acutely with signs and symptoms of heart failure, often with decompensation of pre-existing cardiomyopathy. The most current guidelines classify based on clinical features at initial presentation and are used to both risk stratify and guide the management of haemodynamic compromise. Despite this, AHF remains a diagnosis with a poor prognosis and there is no therapy proven to have long-term mortality benefits. We provide an introduction to AHF and discuss its definition, causes and precipitants. We also present epidemiological and demographic data to suggest that there is significant patient heterogeneity and that AHF is not a single pathology, but rather a range of pathophysiological entities. This poses a challenge when designing clinical trials and may, at least in part, explain why the results in this area have been largely disappointing.

Indexed as

Diagnostic ImagingHeart FailureAcute DiseaseGlobal HealthHumansMorbidityAcute heart failureChallenges in acute heart failureClassification of acute heart failureDecompensated heart failureDefinition of acute heart failureEpidemiology of acute heart failure

Identifiers

PMID28785969
PMCPMC5597697

What OpenQuestion holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.