ArticleAnnals of surgical oncology2017
Predictors of Bowel Function in Long-term Rectal Cancer Survivors with Anastomosis.
Article in Annals of surgical oncology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 23 citations in OpenAlex.
- Quality of Life after Laparoscopic Sphincter-Preserving Total Mesorectal Excision for Low Rectal Cancer: A Single-Center Prospective Cohort Study in Vietnam.Asian Pacific journal of cancer prevention : APJCP · 2025Article
- Quality of life outcomes in colorectal cancer survivors: insights from an observational study at a tertiary cancer center.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2025Observational
- Risk factors influencing sphincter preservation in laparoscopic radical rectal cancer surgery.World journal of gastrointestinal surgery · 2025Article
- A word of caution in the functional monitoring of patients after rectal cancer surgery: a multicentre observational study.Techniques in coloproctology · 2025Observational
- The bowel function instrument for rectal cancer survivors with anastomosis and ostomy.Journal of psychosomatic research · 2024Article
- Long-term bowel functional outcomes following anal sphincter-preserving surgery for upper and middle rectal cancer: a single-center longitudinal study.Annals of coloproctology · 2024Article
- Article
- Development and evaluation of a Japanese prediction model for low anterior resection syndrome after rectal cancer surgery.BMC gastroenterology · 2022Article
- The association of bowel function, participation in life activities, and quality of life in rectal cancer survivors.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2022Article
- SWOG S1820: Altering Intake, Managing Symptoms for bowel dysfunction in survivors of Rectal Cancer (The AIMS-RC intervention trial).Contemporary clinical trials communications · 2021Article
- Immunity, immunotherapy, and rectal cancer: A clinical and translational science review.Translational research : the journal of laboratory and clinical medicine · 2021Review
- Colonic pouch confers better bowel function and similar postoperative outcomes compared to straight anastomosis for low rectal cancer.World journal of gastrointestinal surgery · 2021Article
- Resting vector volume measured before ileostomy reversal may be a predictor of major fecal incontinence in patients with mid or low rectal cancer: a longitudinal cohort study using a prospective clinical database.International journal of colorectal disease · 2019Article
- Mental Health Disorders are More Common in Colorectal Cancer Survivors and Associated With Decreased Overall Survival.American journal of clinical oncology · 2019Article
Corrections and comments
- Erratum issued
Authors and funding
9 authors at 6 institutions in 1 country.
Funding
Abstract
backgroundBowel function in long-term rectal cancer survivors with anastomosis has not been characterized adequately. We hypothesized that bowel function is associated with patient, disease, and treatment characteristics.
methodsThe cohort study included Kaiser Permanente members who were long-term (≥5 years) rectal cancer survivors with anastomosis. Bowel function was scored using the self-administered, 14-item Memorial Sloan-Kettering Cancer Center Bowel Function Index. Patient, cancer, and treatment variables were collected from the electronic medical chart. We used multiple regression to assess the relationship of patient- and treatment-related variables with the bowel function score.
resultsThe study included 381 anastomosis patients surveyed an average 12 years after their rectal cancer surgeries. The total bowel function score averaged 53 (standard deviation, 9; range, 31-70, higher scores represent better function). Independent factors associated with worse total bowel function score included receipt of radiation therapy (yes vs. no: 5.3-unit decrement, p < 0.0001), tumor distance from the anal verge (≤6 cm vs. >6 cm: 3.2-unit decrement, p < 0.01), and history of a temporary ostomy (yes vs. no: 4.0-unit decrement, p < 0.01). One factor measured at time of survey was also associated with worse total bowel function score: ever smoking (2.3-unit decrement, p < 0.05). The regression model explained 20% of the variation in the total bowel function score.
conclusionsLow tumor location, radiation therapy, temporary ostomy during initial treatment, and history of smoking were linked with decreased long-term bowel function following an anastomosis. These results should improve decision-making about surgical options.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.