Evidence map›Paper›PMID 28785812›Full record

SynthesisClinical research in cardiology : official journal of the German Cardiac Society2017

Functional status and quality of life after transcatheter mitral valve repair: a prospective cohort study and systematic review.

Christos Iliadis, Samuel Lee, Kathrin Kuhr, Clemens Metze, Anna-Sophie Matzik, Guido Michels, Volker Rudolph, Stephan Baldus, Roman Pfister

Abstract readSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Clinical research in cardiology : official journal of the German Cardiac Society, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Transcatheter mitral valve edge-to-edge repair for severe mitral regurgitation in patients with HFpEF phenotype.Clinical research in cardiology : official journal of the German Cardiac Society · 2026
    Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Mitral valve leaflet repair with the new PASCAL system: early real-world data from a German multicentre experience.Clinical research in cardiology : official journal of the German Cardiac Society · 2020
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Atrioventricular valve disease: challenges and achievements in percutaneous treatment.Clinical research in cardiology : official journal of the German Cardiac Society · 2018
    Review
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Christos IliadisDepartment III of Internal Medicine, Heart Center, University of Cologne, Kerpener Str. 62, 50937, Cologne, Germany.
Samuel LeeDepartment III of Internal Medicine, Heart Center, University of Cologne, Kerpener Str. 62, 50937, Cologne, Germany.
Kathrin KuhrInstitute of Medical Statistics, Informatics and Epidemiology, University of Cologne, Cologne, Germany.
Clemens MetzeDepartment III of Internal Medicine, Heart Center, University of Cologne, Kerpener Str. 62, 50937, Cologne, Germany.
Anna-Sophie MatzikDepartment III of Internal Medicine, Heart Center, University of Cologne, Kerpener Str. 62, 50937, Cologne, Germany.
Guido MichelsDepartment III of Internal Medicine, Heart Center, University of Cologne, Kerpener Str. 62, 50937, Cologne, Germany.
Volker RudolphDepartment III of Internal Medicine, Heart Center, University of Cologne, Kerpener Str. 62, 50937, Cologne, Germany.
Stephan BaldusDepartment III of Internal Medicine, Heart Center, University of Cologne, Kerpener Str. 62, 50937, Cologne, Germany.
Roman PfisterDepartment III of Internal Medicine, Heart Center, University of Cologne, Kerpener Str. 62, 50937, Cologne, Germany. roman.pfister@uk-koeln.de.ORCID http://orcid.org/0000-0002-4358-5008

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundEstimating the quantitative effect of transcatheter mitral valve repair on functional parameters and quality of life is important for individual treatment decision-making.

methodsWe combined data from a prospective monocentric cohort study (N = 215) with data from a systematic literature review (PubMed search term "mitraclip", till 30.04.2016) on patients undergoing MitraClip with at least mortality after discharge reported as an outcome. Effects on functional parameters were reported as range of mean change.

results36 observational studies and 1 randomized controlled trial were identified. Due to substantial heterogeneity of effect estimates (I

conclusionMitraClip therapy provides improvements in physical capacity, physical and mental functioning and disease-specific quality of life in the majority of patients. However, more comparative and high-quality studies are required for understanding the heterogeneity of results, which is crucial for optimal patient selection.

Indexed as

Heart Valve ProsthesisHemodynamicsMitral Valve InsufficiencyQuality of LifeHumansMitral ValvePostoperative PeriodProspective StudiesFunctionalityMitraClipQuality of life

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.