Evidence map›Paper›PMID 28785469›Full record

ArticleCardiac failure review2017

Global Public Health Burden of Heart Failure.

Gianluigi Savarese, Lars H Lund

15 registry-linked trialsAbstract read
In one paragraph

Article in Cardiac failure review, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 15 registered trials, which are not on this map. Cited by 1,305 papers, 15 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1,305citing papers in PubMed, 15 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02133105 phase3completednot on this map

Efficacy of Intravenous Levosimendan Compared With Dobutamine on Renal Hemodynamics and Function in Chronic Heart Failure

TypeinterventionalSponsorGöteborg UniversityRan2014 to 2017Enrolled33ConditionsCardiorenal SyndromeArmsLevosimendan, Dobutamine
NCT04159454 nacompletednot on this mapstarted 2020, after this paper: background citation

Pacemaker Induced Transient Dyssynchrony for Treating Heart Failure (PITA-HF): Feasibility, Safety, and Tolerability

TypeinterventionalSponsorJohns Hopkins UniversityRan2020 to 2023Enrolled8ConditionsHeart Failure, Dilated CardiomyopathyArmsPITA
NCT05583513 completednot on this mapstarted 2022, after this paper: background citation

Evaluation of the Progression of Disease and Health-related Quality of Life in Ambulatory Heart Failure Patients: A Local Clinic-based Registry

Typeobservational_patient_registrySponsorChinese University of Hong KongRan2022 to 2023Enrolled500ConditionsHeart FailureArmsMLHFQ (Minnesota Living with Heart Failure Questionnaire), KCCQ (the Kansas City Cardiomyopathy Questionnaire)
NCT05655910 narecruitingnot on this mapstarted 2022, after this paper: background citation

Enhanced Nutritional Optimization in LVAD (ENOL) Trial

TypeinterventionalSponsorColumbia UniversityRan2022 to 2027Enrolled50ConditionsHeart Failure, Gut Microbiome, Nutritional DeficiencyArmsEnsure Surgery Immunonutrition shake
NCT05822622 unknown statusnot on this mapstarted 2023, after this paper: background citation

Relationship Between Heart Failure With Preserved Ejection Fraction and Nonalcoholic Fatty Liver Disease.

Typeobservational_patient_registrySponsorSohag UniversityRan2023 to 2023Enrolled100ConditionsHeart Failure With Preserved Ejection Fraction, Non Alcoholic Fatty LiverArmsechocardiography
NCT05861115 nacompletednot on this mapstarted 2023, after this paper: background citation

A Study to Evaluate Accuracy and Validity of the "Chang Gung" Ventricular Systolic Dysfunction Screening Software

TypeinterventionalSponsorChang Gung Memorial HospitalRan2023 to 2023Enrolled1,172ConditionsLeft Ventricular Systolic DysfunctionArms"Chang Gung" Ventricular Systolic Dysfunction Screening Software
NCT06117722 unknown statusnot on this mapstarted 2024, after this paper: background citation

ESTIA: TorasEmide Induced Effect on Quality of Life and Clinical parameterS in paTients With chronIc heArt Failure Receiving Eplerenone. Multicenter, Non-interventional, Prospective, Observational Clinical Study.

TypeobservationalSponsorElpen Pharmaceutical Co. Inc.Ran2024 to 2025Enrolled210ConditionsChronic Heart FailureArmsEplerenone torasemide in chronic heart failure
NCT06298825 unknown statusnot on this mapstarted 2024, after this paper: background citation

Effect of Sarcopenia on Prognosis of Patients With Acute Decompensated Heart Failure: a Prospective, Multi-center, Observational Cohort Study

TypeobservationalSponsorGuangdong Provincial People's HospitalRan2024 to 2026Enrolled500ConditionsAcute Decompensated Heart Failure
NCT06398964 nacompletednot on this mapstarted 2023, after this paper: background citation

Effects of 2-week Ketosis on Myocardial Ketone Body Consumption, Utilization, and External Efficiency in Patients With Chronic Heart Failure

TypeinterventionalSponsorAarhus University HospitalRan2023 to 2025Enrolled12ConditionsHeart Failure With Reduced Ejection FractionArms3-hydroxybutyrat, Isocaloric placebo drink
NCT07008729 naactive not recruitingnot on this mapstarted 2024, after this paper: background citation

Heart Failure Patient Management and Interventions Using Continuous Patient Monitoring Outside Hospitals and Real-world Data

TypeinterventionalSponsorPuerta de Hierro University HospitalRan2024 to 2026Enrolled390ConditionsChronic Heart Failure, Heart Transplant Recipient, Left Ventricular Assist DeviceArmsHeart monitoring tools (data revision), Control (Standard treatment)
NCT07194889 not yet recruitingnot on this mapstarted 2025, after this paper: background citation

External Validation and Recalibration of Heart Failure Risk Models (MAGGIC, GWTG-HF, and SHFM) in Egyptian Patients

Typeobservational_patient_registrySponsorAssiut UniversityRan2025 to 2027Enrolled140ConditionsHeart Failure
NCT07278583 recruitingnot on this mapstarted 2025, after this paper: background citation

Evaluation of Eligibility Criteria for Heart Failure Telemonitoring : Analysis of CARDIAUVERGNE's Cohort

TypeobservationalSponsorUniversity Hospital, Clermont-FerrandRan2025 to 2026Enrolled130ConditionsHeart Failure
NCT07345156 recruitingnot on this mapstarted 2026, after this paper: background citation

Validation of a Combined Score Combining the Lung Ultrasound Score and Lactate at Discharge for Predicting Early Events After Acute Heart Failure

TypeobservationalSponsorUniversity of MonastirRan2026 to 2026Enrolled350ConditionsHeart Failure Acute, Discharge Follow-up Phone Calls, Mortality PredictionArmsLung Ultrasound Score, Lactate Blood Test
NCT07490054 phase1recruitingnot on this mapstarted 2025, after this paper: background citation

An Open-Label, Pilot Clinical Trial To Test The Safety And Feasibility Of Intestinal Microbiota Transplantation In Patients With Chronic Heart Failure

TypeinterventionalSponsorMelana Yuzefpolskaya, MDRan2025 to 2027Enrolled40ConditionsChronic Heart FailureArmsMTP-101-C encapsulated Microbiota, Vancomycin, Neomycin
NCT07561866 completednot on this mapstarted 2018, after this paper: background citation

Impact of Diabetes, Short-term Weight Variability, Heart Failure Etiologies and Other Comorbidities on Survival in a National Telemonitored Heart Failure Cohort

TypeobservationalSponsorSateliaRan2018 to 2024Enrolled16,556ConditionsChronic Heart Failure, Type 2 Diabetes, Diabetes (DM)ArmsDiabetes Status, Comorbidity Burden, Weight variability
3 · Its place in the literature

Who cites it

1,305 citing papers in PubMed, 15 syntheses or guidelines pooled it.

  1. Pooled it
  2. Conduction system pacing vs. biventricular pacing for cardiac resynchronization therapy in heart failure: a systematic review and meta-analysis considering randomized controlled trials and observational studies.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2026
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1,245 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Gianluigi SavareseDivision of Cardiology, Department of Medicine,Karolinska Insitutet, Stockholm, Sweden.
Lars H LundDivision of Cardiology, Department of Medicine,Karolinska Insitutet, Stockholm, Sweden.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Heart failure (HF) is a global pandemic affecting at least 26 million people worldwide and is increasing in prevalence. HF health expenditures are considerable and will increase dramatically with an ageing population. Despite the significant advances in therapies and prevention, mortality and morbidity are still high and quality of life poor. The prevalence, incidence, mortality and morbidity rates reported show geographic variations, depending on the different aetiologies and clinical characteristics observed among patients with HF. In this review we focus on the global epidemiology of HF, providing data about prevalence, incidence, mortality and morbidity worldwide.

Indexed as

clinical characteristicsgeographic differencesHeart failureheart failure with mid-range ejection fractionheart failure with preserved ejection fractionheart failure with reduced ejection fractionincidencemorbiditymortalityprevalence

Identifiers

PMID28785469
PMCPMC5494150

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

and 9 more above

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.