Evidence map›Paper›PMID 28785345›Full record

ArticleOpen access Macedonian journal of medical sciences2017

Basal Cell Carcinoma Surgery: Simple Undermining Approach in Two Patients with Different Tumour Locations.

Georgi Tchernev, Cristiana Voicu, Mara Mihai, Mihai Lupu, Tiberiu Tebeica, Nely Koleva, Uwe Wollina, Torello Lotti, Hristo Mangarov, Ilko Bakardzhiev and 4 more

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Open access Macedonian journal of medical sciences, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Nevus Blue as a Sporadic Finding in a Patient with a Blue Toe?Open access Macedonian journal of medical sciences · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Georgi TchernevMedical Institute of Ministry of Interior (MVR), Department of Dermatology and Dermatologic Surgery, General Skobelev 79, 1606 Sofia, Bulgaria; Onkoderma - Policlinic for Dermatology, Venereology and Dermatologic Surgery, 26 General Skobelev blvd., Sofia, Bulgaria.
Cristiana VoicuDermatology Department, Polisano Clinic, 26Z Timisoara Blvd, Bucharest, Romania.
Mara MihaiOncologic Dermatology and Allergology Department, "Carol Davila" University of Medicine and Pharmacy, 17 Marasti Blvd, Bucharest, Romania.
Mihai LupuDermatology Department, Medas Medical Centre, 41 Nicolae Grigorescu Blvd, Bucharest, Romania.
Tiberiu TebeicaDr Leventer Centre, 13-17 Sevastopol Street, Ste. 204, Bucharest 010991, Romania.
Nely KolevaMedical Institute of Ministry of Interior (MVR), Department of Dermatology and Dermatologic Surgery, General Skobelev 79, 1606 Sofia, Bulgaria.
Uwe WollinaDepartment of Dermatology and Allergology, Academic Friedrichstrasse 41, 01067, Dresden, Germany.
Torello LottiChair of Dermatology, University of Rome G. Marconi, Rome, Italy.
Hristo MangarovMedical Institute of Ministry of Interior (MVR), Department of Dermatology and Dermatologic Surgery, General Skobelev 79, 1606 Sofia, Bulgaria.
Ilko BakardzhievMedical College, Varna, Bulgaria.
Jacopo LottiDepartment of Nuclear, Subnuclear and Radiation Physics, University of Rome "G. Marconi", Rome, Italy.
Katlein FrançaInstitute for Bioethics & Health Policy; Department of Dermatology & Cutaneous Surgery; Department of Psychiatry & Behavioral Sciences, University of Miami Miller School of Medicine - Miami, FL, USA.
Atanas BatashkiAbdominal and Thoracic Surgery, Department of Special Surgery, Medical University of Plovdiv, bul. "Peshtersko shose" Nr 66, 4000 Plovdiv, Bulgaria.
James W PattersonDepartment of Pathology, University of Virginia Health System, 1215 Lee Street, Box 800214, Charlottesville, VA 22908, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Basal cell carcinoma (BCC) is the most common human malignancy, accounting for the majority of all non-melanoma skin cancers (NMSC). In the past several decades the worldwide incidence of BCC has constantly been increasing. Even though it is a slow growing tumour that, left untreated, rarely metastasizes, it has a distinctive invasive growth pattern, posing a considerable risk for local invasion and destruction of underlying tissues, such as muscle, cartilage, bone or vital structures. Advanced BCCs include such locally invasive or metastatic tumours. Complete surgical excision is the standard therapy for most uncomplicated BCC cases with good prognosis and cure rates. Treatment of advanced forms of BCCs poses significant therapeutic challenges, most often requiring complicated surgery, radiotherapy, and/or targeted therapies directed towards the sonic hedgehog signalling pathway (SHH). We present two cases of large BCCs located on the scalp and posterior thorax, which underwent surgical excision with clear margins, followed by reconstruction of the defect after extensive undermining of the skin.

Indexed as

basal cell carcinomaextendable plasticsurgerytreatmentundermining

Identifiers

PMID28785345
PMCPMC5535670

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.