Evidence map›Paper›PMID 28785323›Full record

ArticleOpen access Macedonian journal of medical sciences2017

Pyogenic Granuloma - A Common Benign Vascular Tumor with Variable Clinical Presentation: New Findings and Treatment Options.

Uwe Wollina, Dana Langner, Katlein França, Serena Gianfaldoni, Torello Lotti, Georgi Tchernev

Open access · diamondAbstract read
In one paragraph

Article in Open access Macedonian journal of medical sciences, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
7.2field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 142 citations in OpenAlex.

  1. Article
  2. Review
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  4. Pyogenic Granuloma Diagnosis and Management: A Practical Review.Plastic and reconstructive surgery. Global open · 2024
    Review
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  10. [Benign skin neoplasms in children].Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete · 2022
    Review
  11. Article
  12. Review
  13. Management of Pyogenic Granulomas Following Burn Wounds.World journal of plastic surgery · 2021
    Article
  14. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Uwe WollinaDepartment of Dermatology and Allergology, Academic Teaching Hospital Dresden-Friedrichstadt, Dresden, Germany.
Dana LangnerDepartment of Dermatology and Allergology, Academic Teaching Hospital Dresden-Friedrichstadt, Dresden, Germany.
Katlein FrançaDepartment of Dermatology & Cutaneous Surgery, and Department of Psychiatry & Behavioral Sciences, Institute for Bioethics & Health Policy, University of Miami Miller School of Medicine, Miami, FL, USA.
Serena GianfaldoniDermatological Department University of Pisa, Pisa, Italy.
Torello LottiCentro Studi per la Ricerca Multidisciplinare e Rigenerativa, Università Degli Studi "G. Marconi", Rome, Italy.
Georgi TchernevMedical Institute of Ministry of Interior (MVR), Department of Dermatology, Venereology and Dermatologic Surgery, Sofia, and Onkoderma-Policlinic for Dermatology and Dermatologic Surgery, Sofia, Bulgaria.
Städtisches Klinikum Dresden · DEMarconi University · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pyogenic granuloma is a common benign vascular tumour occurring in all ages. Both skin and mucous membranes can be affected. Of pathogenetic importance are trauma, BRAF mutations and probably herpes virus type 1, Orf virus and/or human papilloma virus type 2. The tumour consists of capillary proliferations, venules and fibromyxoid stroma. The development of a lesion occurs in three stages and bleeding is a common symptom. The tumour can mimic various other vascular lesions, solid tumours, and soft tissue infections. In recent years, targeted tumour therapies have become the most common cause of drug-induced pyogenic granulomas. The backbone of treatment is surgical procedures including laser therapy. New developments in medical drug therapy include topical and systemic beta-adrenergic receptor antagonists timolol and propranolol. Drug therapy is an alternative for young children, ocular and periungual pyogenic granuloma.

Indexed as

benign vascular tumoursbeta-adrenergic receptor antagonistsBRAF mutationsPyogenic granulomasurgeryvirus

Identifiers

PMID28785323
PMCPMC5535648
OpenAlexW2737798145

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.