Evidence map›Paper›PMID 28785222›Full record

ArticleFrontiers in pharmacology2017

Inhibition of PAI-1 Activity by Toddalolactone as a Mechanism for Promoting Blood Circulation and Removing Stasis by Chinese Herb

Bo Yu, Guangping Zhang, Lingling Jin, Bo Zhang, Dong Yan, Hong Yang, Zuguang Ye, Tonghui Ma

Open access · goldAbstract read
In one paragraph

Article in Frontiers in pharmacology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Article
  6. Pharmaceutical biology · 2022
    Article
  7. Article
  8. Molecules (Basel, Switzerland) · 2021
    Review
  9. Article
  10. Review
  11. Article
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Bo YuSchool of Life Sciences, Liaoning Provincial Key Laboratory of Biotechnology and Drug Discovery, Liaoning Normal UniversityDalian, China.
Guangping ZhangInstitute of Chinese Materia Medica, China Academy of Chinese Medical SciencesBeijing, China.
Lingling JinCollege of Basic Medical Sciences, Dalian Medical UniversityDalian, China.
Bo ZhangCollege of Basic Medical Sciences, Dalian Medical UniversityDalian, China.
Dong YanSchool of Life Sciences, Liaoning Provincial Key Laboratory of Biotechnology and Drug Discovery, Liaoning Normal UniversityDalian, China.
Hong YangSchool of Life Sciences, Liaoning Provincial Key Laboratory of Biotechnology and Drug Discovery, Liaoning Normal UniversityDalian, China.
Zuguang YeInstitute of Chinese Materia Medica, China Academy of Chinese Medical SciencesBeijing, China.
Tonghui MaCollege of Basic Medical Sciences, Dalian Medical UniversityDalian, China.
Dalian Medical University · CNLiaoning Normal University · CNChinese Academy of Medical Sciences & Peking Union Medical College · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Traditional Chinese medicine has been used to treat a variety of human diseases for many centuries.

Indexed as

fibrinolysisPAI-1PAI-1 inhibitorpharmacologytoddalolactone

Identifiers

PMID28785222
PMCPMC5519579
OpenAlexW2738768419

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.