Evidence map›Paper›PMID 28785148›Full record

ArticleWorld journal of gastroenterology2017

Perinatal transmission in infants of mothers with chronic hepatitis B in California.

Jennifer C Burgis, Darryl Kong, Catheryn Salibay, Jennifer Zipprich, Kathleen Harriman, Samuel So

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in World journal of gastroenterology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.5field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Jennifer C BurgisJennifer C Burgis, Department of Pediatrics, Stanford University, Palo Alto, CA 94304, United States.
Darryl KongJennifer C Burgis, Department of Pediatrics, Stanford University, Palo Alto, CA 94304, United States.
Catheryn SalibayJennifer C Burgis, Department of Pediatrics, Stanford University, Palo Alto, CA 94304, United States.
Jennifer ZipprichJennifer C Burgis, Department of Pediatrics, Stanford University, Palo Alto, CA 94304, United States.
Kathleen HarrimanJennifer C Burgis, Department of Pediatrics, Stanford University, Palo Alto, CA 94304, United States.
Samuel SoJennifer C Burgis, Department of Pediatrics, Stanford University, Palo Alto, CA 94304, United States.
California Department of Public Health · USPalo Alto University · USStanford University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo evaluate maternal hepatitis B virus (HBV) DNA as risk for perinatal HBV infection among infants of HBV-infected women in California.

methodsRetrospective analysis among infants born to hepatitis B surface antigen (HBsAg)-positive mothers who received post vaccination serologic testing (PVST) between 2005 and 2011 in California. Demographic information was collected from the California Department of Public Health Perinatal Hepatitis B Program databaseand matched to birth certificate records. HBV DNA level and hepatitis B e antigen (HBeAg) status were obtained from three large commercial laboratories in California and provider records if available and matched to mother infant pairs. Univariate analysis compared infected and uninfected infants. Multivariate analysis was restricted to infected infants and controls with complete maternal HBV DNA results using a predefined high HBV DNA level of > 2 × 10

resultsA total of 17687 infants were born to HBsAg positive mothers in California between Jan 1 2005 and Dec 31, 2011. Among 11473 infants with PVST, only 125 (1.1%) were found to be HBV infected. Among these infected infants, lapses in Advisory Committee on Immunization Practices recommended post exposure prophylaxis (PEP) occurred in only 9 infants. However, PEP errors were not significantly different between infected and uninfected infants. Among the 347 uninfected and infected infants who had maternal HBeAg and HBV DNA level, case-control analysis found HBeAg positivity (70.4%

conclusionIn California, transmission is low and most infected infants receive appropriate PEP and vaccination. Maternal HBV DNA ≥ 2 × 10

Indexed as

Infectious Disease Transmission, VerticalAdultCaliforniaCase-Control StudiesDNA, ViralFemaleHepatitis B, ChronicHepatitis B e AntigensHepatitis B Surface AntigensHepatitis B virusHumansIncidenceInfant, NewbornMaleMothersPost-Exposure ProphylaxisDNA, ViralHepatitis B e AntigensHepatitis B Surface AntigensHepatitis BHepatitis B virus DNAPerinatal transmissionPost-vaccine serology testingPregnancyVaccination

Identifiers

PMID28785148
PMCPMC5526764
OpenAlexW2736500933

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.