Evidence map›Paper›PMID 28785146›Full record

ArticleWorld journal of gastroenterology2017

Anti-oxidant and anti-inflammatory effects of hydrogen-rich water alleviate ethanol-induced fatty liver in mice.

Ching-Pin Lin, Wen-Chen Chuang, Fung-Jou Lu, Chih-Yen Chen

Open access · hybridAbstract readComparative Study
In one paragraph

Article in World journal of gastroenterology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed, 1 pooled it
5.5field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 1 synthesis or guideline pooled it, 54 citations in OpenAlex.

  1. Pooled it
  2. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Ching-Pin LinChing-Pin Lin, Institute of Biochemistry, Microbiology and Immunology, Chung Shan Medical University, Taichung 402, Taiwan.
Wen-Chen ChuangChing-Pin Lin, Institute of Biochemistry, Microbiology and Immunology, Chung Shan Medical University, Taichung 402, Taiwan.
Fung-Jou LuChing-Pin Lin, Institute of Biochemistry, Microbiology and Immunology, Chung Shan Medical University, Taichung 402, Taiwan.
Chih-Yen ChenChing-Pin Lin, Institute of Biochemistry, Microbiology and Immunology, Chung Shan Medical University, Taichung 402, Taiwan.
Chung Shan Medical University · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo investigate the effects of hydrogen-rich water (HRW) treatment on prevention of ethanol (EtOH)-induced early fatty liver in mice.

methods

resultsThe

conclusionHRW protects against chronic EtOH-induced liver injury, possibly by inducing acyl ghrelin to suppress the pro-inflammatory cytokines TNF-α and IL-6 and induce IL-10 and IL-22, thus activating antioxidant enzymes against oxidative stress.

Indexed as

Alanine TransaminaseAnimalsAntioxidantsAspartate AminotransferasesCytokinesDisease Models, AnimalEthanolFatty Liver, AlcoholicFemaleGhrelinGlutathioneGlutathione PeroxidaseHumansHydrogenHydrogen PeroxideLiverAlanine TransaminaseAntioxidantsAspartate AminotransferasesCytokinesEthanolGhrelinGlutathioneGlutathione PeroxidaseHydrogenHydrogen PeroxideMalondialdehydeProtective AgentsSilymarinSuperoxide DismutaseWaterAcyl ghrelinAntioxidantChronic plus binge EtOH feedingFemale miceHydrogenProtective cytokine

Identifiers

PMID28785146
PMCPMC5526762
OpenAlexW2736639322

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.