ArticleScientific reports2017
Genomic surveillance reveals low prevalence of livestock-associated methicillin-resistant Staphylococcus aureus in the East of England.
Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
14 citing papers in PubMed.
- Joining Forces against Antibiotic Resistance: The One Health Solution.Pathogens (Basel, Switzerland) · 2023Review
- The Epidemiology of Animal-Associated Methicillin-ResistantAntibiotics (Basel, Switzerland) · 2023Review
- Antimicrobial resistance in methicillin-resistant staphylococcus aureus.Saudi journal of biological sciences · 2023Review
- A review of horses as a source of spreading livestock-associated methicillin-resistantVeterinary world · 2022Review
- Wild Animals Are Reservoirs and Sentinels ofAntibiotics (Basel, Switzerland) · 2021Review
- Antimicrobial Resistance and Genetic Lineages ofAnimals : an open access journal from MDPI · 2021Article
- Prevalence and characterization ofJAC-antimicrobial resistance · 2021Article
- Genomic Analysis ofFrontiers in microbiology · 2021Article
- HumanMicroorganisms · 2020Review
- Marked Presence of Methicillin-ResistantAnimals : an open access journal from MDPI · 2020Article
- A mecC allotype, mecC3, in the CoNS Staphylococcus caeli, encoded within a variant SCCmecC.The Journal of antimicrobial chemotherapy · 2019Article
- Livestock-Associated Methicillin-ResistantFrontiers in microbiology · 2019Article
- Whole-genome epidemiology, characterisation, and phylogenetic reconstruction of Staphylococcus aureus strains in a paediatric hospital.Genome medicine · 2018Article
- Characterization of Livestock-Associated Methicillin-ResistantFrontiers in microbiology · 2018Article
Corrections and comments
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Authors and funding
8 authors.
Funding
Abstract
Livestock-associated methicillin-resistant Staphylococcus aureus (LA-MRSA) is an emerging problem in many parts of the world. LA-MRSA has been isolated previously from animals and humans in the United Kingdom (UK), but the prevalence is unknown. The aim of this study was to determine the prevalence and to describe the molecular epidemiology of LA-MRSA isolated in the East of England (broadly Cambridge and the surrounding area). We accessed whole genome sequence data for 2,283 MRSA isolates from 1,465 people identified during a 12-month prospective study between 2012 and 2013 conducted in the East of England, United Kingdom. This laboratory serves four hospitals and 75 general practices. We screened the collection for multilocus sequence types (STs) and for host specific resistance and virulence factors previously associated with LA-MRSA. We identified 13 putative LA-MRSA isolates from 12 individuals, giving an estimated prevalence of 0.82% (95% CI 0.47% to 1.43%). Twelve isolates were mecC-MRSA (ten CC130, one ST425 and one ST1943) and single isolate was ST398. Our data demonstrate a low burden of LA-MRSA in the East of England, but the detection of mecC-MRSA and ST398 indicates the need for vigilance. Genomic surveillance provides a mechanism to detect and track the emergence and spread of MRSA clones of human importance.
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