Evidence map›Paper›PMID 28785082›Full record

ArticleScientific reports2017

Standardization of electroencephalography for multi-site, multi-platform and multi-investigator studies: insights from the canadian biomarker integration network in depression.

Faranak Farzan, Sravya Atluri, Matthew Frehlich, Prabhjot Dhami, Killian Kleffner, Rae Price, Raymond W Lam, Benicio N Frey, Roumen Milev, Arun Ravindran and 13 more

Registry-linked trialOpen access · goldAbstract readMulticenter Study
In one paragraph

Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05017311 (Optimized Predictive Treatment In Medications for Unipolar Major Depression), which is not on this map. Cited by 26 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 2 pooled it
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05017311 phase4recruitingnot on this mapstarted 2023, after this paper: background citation

Optimized Predictive Treatment In Medications for Unipolar Major Depression (OPTIMUM-D)

TypeinterventionalSponsorNova Scotia Health AuthorityRan2023 to 2029Enrolled400ConditionsMajor Depressive DisorderArmsEscitalopram, Brexpiprazole
3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 2 syntheses or guidelines pooled it, 49 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Dementia ConnEEGtome: Towards multicentric harmonization of EEG connectivity in neurodegeneration.International journal of psychophysiology : official journal of the International Organization of Psychophysiology · 2022
    Review
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

23 authors at 11 institutions in 2 countries.

Faranak FarzanCentre for Addiction and Mental Health, 1001 Queen St. W, Toronto, ON, M6J 1A8, Canada. ffarzan@sfu.ca.ORCID 0000-0001-9249-2994
Sravya AtluriCentre for Addiction and Mental Health, 1001 Queen St. W, Toronto, ON, M6J 1A8, Canada.
Matthew FrehlichCentre for Addiction and Mental Health, 1001 Queen St. W, Toronto, ON, M6J 1A8, Canada.
Prabhjot DhamiCentre for Addiction and Mental Health, 1001 Queen St. W, Toronto, ON, M6J 1A8, Canada.
Killian KleffnerUniversity of British Columbia and Vancouver Coastal Health Authority, 2255 Wesbrook Mall, Vancouver, BC, V6T 2A1, Canada.
Rae PriceUniversity Health Network, 399 Bathurst Street, Toronto, ON, M5T 2S8, Canada.
Raymond W LamUniversity of British Columbia and Vancouver Coastal Health Authority, 2255 Wesbrook Mall, Vancouver, BC, V6T 2A1, Canada.
Benicio N FreyMcMaster University, and St. Joseph's Healthcare Hamilton, 1280 Main Street West, Hamilton, ON, L8S 4L8, Canada.
Roumen MilevQueen's University, Providence Care, Mental Health Services, 752 King Street West, Kingston, ON, K7L 4X3, Canada.ORCID 0000-0001-6884-171X
Arun RavindranCentre for Addiction and Mental Health, 1001 Queen St. W, Toronto, ON, M6J 1A8, Canada.
Mary Pat McAndrewsDepartment of Psychiatry, University of Toronto, 250 College Street, 8th floor, Toronto, ON, M5T 1R8, Canada.
Willy WongThe Edward S. Rogers Sr. Department of Electrical & Computer Engineering, University of Toronto, 10 King's College Road, Toronto, ON, M5S 3G4, Canada.
Daniel BlumbergerCentre for Addiction and Mental Health, 1001 Queen St. W, Toronto, ON, M6J 1A8, Canada.
Zafiris J DaskalakisCentre for Addiction and Mental Health, 1001 Queen St. W, Toronto, ON, M6J 1A8, Canada.
Fidel Vila-RodriguezUniversity of British Columbia and Vancouver Coastal Health Authority, 2255 Wesbrook Mall, Vancouver, BC, V6T 2A1, Canada.
Esther AlonsoUniversity of British Columbia and Vancouver Coastal Health Authority, 2255 Wesbrook Mall, Vancouver, BC, V6T 2A1, Canada.
Colleen A BrennerLoma Linda University, 24851 Circle Dr, Loma Linda, CA, 92354, USA.
Mario LiottiSimon Fraser University, 8888 University Dr, Burnaby, BC, V5A 1S6, Canada.
Moyez DharseeIndoc Research, 258 Adelaide St. East, Suite 200, Toronto, ON, M5A 1N1, Canada.
Stephen R ArnottRotman Research Institute at Baycrest Centre, 3560 Bathurst Street, Toronto, ON, M6A 2E1, Canada.
Kenneth R EvansIndoc Research, 258 Adelaide St. East, Suite 200, Toronto, ON, M5A 1N1, Canada.
Susan RotzingerDepartment of Psychiatry, University of Toronto, 250 College Street, 8th floor, Toronto, ON, M5T 1R8, Canada.
Sidney H KennedyDepartment of Psychiatry, University of Toronto, 250 College Street, 8th floor, Toronto, ON, M5T 1R8, Canada.
Centre for Addiction and Mental Health · CAVancouver Coastal Health · CAUniversity Health Network · CAQueen's University · CABaycrest Hospital · CAIndoc Research · CALoma Linda University · USSimon Fraser University · CASt. Joseph’s Healthcare Hamilton · CASt. Michael's Hospital · CAUniversity of Toronto · CA

Funding

CIHR
6 · The paper itself

Abstract

Subsequent to global initiatives in mapping the human brain and investigations of neurobiological markers for brain disorders, the number of multi-site studies involving the collection and sharing of large volumes of brain data, including electroencephalography (EEG), has been increasing. Among the complexities of conducting multi-site studies and increasing the shelf life of biological data beyond the original study are timely standardization and documentation of relevant study parameters. We present the insights gained and guidelines established within the EEG working group of the Canadian Biomarker Integration Network in Depression (CAN-BIND). CAN-BIND is a multi-site, multi-investigator, and multi-project network supported by the Ontario Brain Institute with access to Brain-CODE, an informatics platform that hosts a multitude of biological data across a growing list of brain pathologies. We describe our approaches and insights on documenting and standardizing parameters across the study design, data collection, monitoring, analysis, integration, knowledge-translation, and data archiving phases of CAN-BIND projects. We introduce a custom-built EEG toolbox to track data preprocessing with open-access for the scientific community. We also evaluate the impact of variation in equipment setup on the accuracy of acquired data. Collectively, this work is intended to inspire establishing comprehensive and standardized guidelines for multi-site studies.

Indexed as

Access to InformationAntidepressive AgentsAripiprazoleBrain MappingCanadaCitalopramData CurationDepressive DisorderElectroencephalographyGuidelines as TopicHumansMedical Informatics ComputingProblem SolvingResearch DesignResearch PersonnelTreatment OutcomeAntidepressive AgentsAripiprazoleCitalopram

Identifiers

PMID28785082
PMCPMC5547036
OpenAlexW2741843236

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.