ArticleScientific reports2017
Twisting of DNA Origami from Intercalators.
Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
12 citing papers in PubMed, 24 citations in OpenAlex.
- Left-Handed Helices in DNA Nanotechnology.JACS Au · 2026Review
- Predicting the effect of binding molecules on the shape and mechanical properties of structured DNA assemblies.Nature communications · 2024Article
- Strategies to Reduce Promoter-Independent Transcription of DNA Nanostructures and Strand Displacement Complexes.ACS synthetic biology · 2024Review
- Salting-Out of DNA Origami Nanostructures by Ammonium Sulfate.International journal of molecular sciences · 2022Article
- Modulating the chemo-mechanical response of structured DNA assemblies through binding molecules.Nucleic acids research · 2021Article
- Understanding Förster Resonance Energy Transfer in the Sheet Regime with DNA Brick-Based Dye Networks.ACS nano · 2021Article
- DNA origami patterning of synthetic T cell receptors reveals spatial control of the sensitivity and kinetics of signal activation.Proceedings of the National Academy of Sciences of the United States of America · 2021Article
- Programming ultrasensitive threshold response through chemomechanical instability.Nature communications · 2021Article
- Conformational Control of DNA Origami by DNA Oligomers, Intercalators and UV Light.Methods and protocols · 2021Article
- A unified computational view of DNA duplex, triplex, quadruplex and their donor-acceptor interactions.Nucleic acids research · 2021Article
- Static DNA Nanostructures For Cancer Theranostics: Recent Progress In Design And Applications.Nanotechnology, science and applications · 2019Article
- Switchable DNA-origami nanostructures that respond to their environment and their applications.Biophysical reviews · 2018Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 2 institutions in 1 country.
Funding
Abstract
DNA nanostructures represent the confluence of materials science, computer science, biology, and engineering. As functional assemblies, they are capable of performing mechanical and chemical work. In this study, we demonstrate global twisting of DNA nanorails made from two DNA origami six-helix bundles. Twisting was controlled using ethidium bromide or SYBR Green I as model intercalators. Our findings demonstrate that DNA nanorails: (i) twist when subjected to intercalators and the amount of twisting is concentration dependent, and (ii) twisting saturates at elevated concentrations. This study provides insight into how complex DNA structures undergo conformational changes when exposed to intercalators and may be of relevance when exploring how intercalating drugs interact with condensed biological structures such as chromatin and chromosomes, as well as chromatin analogous gene expression devices.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.