Evidence map›Paper›PMID 28785040›Full record

ArticleScientific reports2017

Driven translocation of a semi-flexible polymer through a nanopore.

Jalal Sarabadani, Timo Ikonen, Harri Mökkönen, Tapio Ala-Nissila, Spencer Carson, Meni Wanunu

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jalal SarabadaniDepartment of Applied Physics and COMP Center of Excellence, Aalto University School of Science, P.O. Box 11000, FI-00076, Aalto, Espoo, Finland. jalal.sarabadani@aalto.fi.
Timo IkonenVTT Technical Research Centre of Finland Ltd., P.O. Box 1000, FI-02044, VTT, Finland.
Harri MökkönenDepartment of Applied Physics and COMP Center of Excellence, Aalto University School of Science, P.O. Box 11000, FI-00076, Aalto, Espoo, Finland.
Tapio Ala-NissilaDepartment of Applied Physics and COMP Center of Excellence, Aalto University School of Science, P.O. Box 11000, FI-00076, Aalto, Espoo, Finland.
Spencer CarsonDepartment of Physics, Northeastern University, Boston, MA, 02115, United States.
Meni WanunuDepartment of Physics, Northeastern University, Boston, MA, 02115, United States.

Funding

Direct picogram DNA and RNA sequencing using nanopore Zero-mode waveguidesR01HG009186 · NHGRI · NORTHEASTERN UNIVERSITY · PI WANUNU, MENI · 2016 to 2019
$2.3M
NHGRI NIH HHS R01 HG009186
6 · The paper itself

Abstract

We study the driven translocation of a semi-flexible polymer through a nanopore by means of a modified version of the iso-flux tension propagation theory, and extensive molecular dynamics (MD) simulations. We show that in contrast to fully flexible chains, for semi-flexible polymers with a finite persistence length [Formula: see text] the trans side friction must be explicitly taken into account to properly describe the translocation process. In addition, the scaling of the end-to-end distance R

Indexed as

NanoporesDNAModels, ChemicalMolecular Dynamics SimulationDNA

Identifiers

PMID28785040
PMCPMC5547125

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.