Evidence map›Paper›PMID 28785015›Full record

ArticleScientific reports2017

Grating-based phase-contrast and dark-field computed tomography: a single-shot method.

Maximilian von Teuffenbach, Thomas Koehler, Andreas Fehringer, Manuel Viermetz, Bernhard Brendel, Julia Herzen, Roland Proksa, Ernst J Rummeny, Franz Pfeiffer, Peter B Noël

Abstract read
In one paragraph

Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

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  6. Dark-field computed tomography reaches the human scale.Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Maximilian von TeuffenbachChair of Biomedical Physics, Department of Physics and Munich School of Bioengineering, Technical University of Munich, 85748, Garching, Germany. Maximilian.Teuffenbach@tum.de.
Thomas KoehlerPhilips GmbH Innovative Technologies, Research Laboratories, 22335, Hamburg, Germany.
Andreas FehringerChair of Biomedical Physics, Department of Physics and Munich School of Bioengineering, Technical University of Munich, 85748, Garching, Germany.
Manuel ViermetzChair of Biomedical Physics, Department of Physics and Munich School of Bioengineering, Technical University of Munich, 85748, Garching, Germany.
Bernhard BrendelPhilips GmbH Innovative Technologies, Research Laboratories, 22335, Hamburg, Germany.
Julia HerzenChair of Biomedical Physics, Department of Physics and Munich School of Bioengineering, Technical University of Munich, 85748, Garching, Germany.ORCID 0000-0002-9456-1591
Roland ProksaPhilips GmbH Innovative Technologies, Research Laboratories, 22335, Hamburg, Germany.
Ernst J RummenyDepartment of Diagnostic and Interventional Radiology, Klinikum rechts der Isar, Technical University of Munich, 81675, Munich, Germany.
Franz PfeifferChair of Biomedical Physics, Department of Physics and Munich School of Bioengineering, Technical University of Munich, 85748, Garching, Germany.
Peter B NoëlChair of Biomedical Physics, Department of Physics and Munich School of Bioengineering, Technical University of Munich, 85748, Garching, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Grating-based X-ray interferometry offers vast potential for imaging materials and tissues that are not easily visualised using conventional X-ray imaging. Tomographic reconstruction based on X-ray interferometric data provides not only access to the attenuation coefficient of an object, but also the refractive index and information about ultra-small-angle scattering. This improved functionality comes at the cost of longer measurement times because existing projection-based signal extraction algorithms require not only a single measurement per projection angle but several with precise grating movements in between. This obstacle hinders the adaptation of grating-based interferometry into a continuously rotating gantry. Several solutions to this problem have been proposed but all suffer from major drawbacks. We present results using an iterative reconstruction algorithm working directly on the interferograms. The suggested direct approach enables improved image quality, since interpolations and unnecessary assumptions about the object are circumvented. Our results demonstrate that it is possible to successfully reconstruct the linear attenuation coefficient, the refractive index and the linear diffusion coefficient, which is a measure related to ultra-small-angle scattering, using a single measurement per projection angle and without any grating movements. This is a milestone for future clinical implementation of grating-based phase-contrast and dark-field contrast X-ray computed tomography.

Identifiers

PMID28785015
PMCPMC5547164

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.