Evidence map›Paper›PMID 28784932›Full record

ArticleInfection and immunity2017

Fatal Pertussis in the Neonatal Mouse Model Is Associated with Pertussis Toxin-Mediated Pathology beyond the Airways.

Karen M Scanlon, Yael G Snyder, Ciaran Skerry, Nicholas H Carbonetti

Open access · bronzeAbstract read
In one paragraph

Article in Infection and immunity, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
2.9field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 53 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Neonatal infection withiScience · 2025
    Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Generating enhanced mucosal immunity againstFrontiers in immunology · 2023
    Article
  14. InvasiveOpen forum infectious diseases · 2022
    Article
  15. Article
  16. Article
  17. Review
  18. Non-primate animal models for pertussis: back to the drawing board?Applied microbiology and biotechnology · 2022
    Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Karen M ScanlonDepartment of Microbiology and Immunology, University of Maryland School of Medicine, Baltimore, Maryland, USA.
Yael G SnyderDepartment of Microbiology and Immunology, University of Maryland School of Medicine, Baltimore, Maryland, USA.
Ciaran SkerryDepartment of Microbiology and Immunology, University of Maryland School of Medicine, Baltimore, Maryland, USA.
Nicholas H CarbonettiDepartment of Microbiology and Immunology, University of Maryland School of Medicine, Baltimore, Maryland, USA ncarbonetti@som.umaryland.edu.
University of Maryland, Baltimore · US

Funding

Exacerbation of pertussis airway inflammation and pathology by pertussis toxinR01AI101055 · NIAID · UNIVERSITY OF MARYLAND BALTIMORE · PI CARBONETTI, NICHOLAS H · 2013 to 2017
$1.9M
Host-targeted therapeutics for pertussis in infantsR21AI117095 · NIAID · UNIVERSITY OF MARYLAND BALTIMORE · PI CARBONETTI, NICHOLAS H · 2016 to 2017
$424k
Exacerbation of pertussis airway inflammation and pathology by pertussis toxinR56AI101055 · NIAID · UNIVERSITY OF MARYLAND BALTIMORE · PI CARBONETTI, NICHOLAS H · 2012 to 2012
$401k
NIAID NIH HHS R01 AI101055NIAID NIH HHS R21 AI117095NIAID NIH HHS R56 AI101055
6 · The paper itself

Abstract

In infants,

Indexed as

Host-Pathogen InteractionsAge FactorsAnimalsAnimals, NewbornBordetella pertussisDisease Models, AnimalHumansInfantLeukocytosisLungMiceMice, Inbred BALB CNeutrophilsPertussis ToxinSurvival AnalysisT-LymphocytesPertussis ToxinBordetella pertussisdisseminated infectionleukocytosisneonatal infectionpertussis toxin

Identifiers

PMID28784932
PMCPMC5649019
OpenAlexW2742935039

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.