Evidence map›Paper›PMID 28784928›Full record

ArticleInfection and immunity2017

Transforming Growth Factor β1/SMAD Signaling Pathway Activation Protects the Intestinal Epithelium from Clostridium difficile Toxin A-Induced Damage.

Christianne Maria Tinoco-Veras, Ana Angélica Q A Santos, Joice Stipursky, Marcelo Meloni, Ana Paula Bérgamo Araujo, Danielle Abreu Foschetti, Diana López-Ureña, Carlos Quesada-Gómez, Renata F C Leitão, Flávia Carvalho Alcantara Gomes and 1 more

Open access · bronzeAbstract read
In one paragraph

Article in Infection and immunity, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 30 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Recent advances in the liposomal nanovesicles based immunotherapy in the treatment of cancer: A review.Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2023
    Review
  5. Pleiotropic effects ofFrontiers in microbiology · 2023
    Article
  6. Article
  7. Article
  8. Article
  9. S100B Inhibition Attenuates Intestinal Damage and Diarrhea Severity DuringFrontiers in cellular and infection microbiology · 2021
    Article
  10. Review
  11. Frontiers in microbiology · 2020
    Article
  12. Burn-Induced Impairment of Ileal Muscle Contractility Is Associated with Increased Extracellular Matrix Components.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2020
    Article
  13. Article
  14. Review
  15. Article
  16. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 2 countries.

Christianne Maria Tinoco-VerasDepartamento de Morfologia, Faculdade de Medicina, Universidade Federal do Ceará, Fortaleza, Brazil.
Ana Angélica Q A SantosDepartamento de Morfologia, Faculdade de Medicina, Universidade Federal do Ceará, Fortaleza, Brazil.
Joice StipurskyInstituto de Ciências Biomédicas, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil.
Marcelo MeloniInstituto de Ciências Biomédicas, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil.
Ana Paula Bérgamo AraujoInstituto de Ciências Biomédicas, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil.
Danielle Abreu FoschettiDepartamento de Morfologia, Faculdade de Medicina, Universidade Federal do Ceará, Fortaleza, Brazil.ORCID http://orcid.org/0000-0002-4213-9786
Diana López-UreñaLaboratorio de Investigación en Bacteriología Anaerobia, Facultad de Microbiología, and Centro de Investigación en Enfermedades Tropicales, Universidad de Costa Rica, San José, Costa Rica.
Carlos Quesada-GómezLaboratorio de Investigación en Bacteriología Anaerobia, Facultad de Microbiología, and Centro de Investigación en Enfermedades Tropicales, Universidad de Costa Rica, San José, Costa Rica.
Renata F C LeitãoDepartamento de Morfologia, Faculdade de Medicina, Universidade Federal do Ceará, Fortaleza, Brazil.
Flávia Carvalho Alcantara GomesInstituto de Ciências Biomédicas, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil fgomes@icb.ufrj.br gerlybrito@hotmail.com.
Gerly Anne de Castro BritoDepartamento de Morfologia, Faculdade de Medicina, Universidade Federal do Ceará, Fortaleza, Brazil fgomes@icb.ufrj.br gerlybrito@hotmail.com.
Universidade Federal do Rio de Janeiro · BRUniversidade Federal do Ceará · BRUniversidad de Costa Rica · CR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Signal TransductionAnimalsBacterial ProteinsBacterial ToxinsCell DeathCell LineCell SurvivalClostridioides difficileEnterotoxinsIleumIntestinal MucosaIntestinesMiceSmad ProteinsTransforming Growth Factor beta1Bacterial ProteinsBacterial ToxinsEnterotoxinsSmad ProteinstcdA protein, Clostridium difficileTransforming Growth Factor beta1Clostridium difficileSMADSMAD transcription factorsTGF-βtoxin A

Identifiers

PMID28784928
PMCPMC5607421
OpenAlexW2744853370

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.