Evidence map›Paper›PMID 28784871›Full record

ArticleBMJ case reports2017

Over-the-counter natural products in cardiac surgery: a case of ginseng-related massive perioperative bleeding.

Alessandro Viviano, Duncan Steele, Mark Edsell, Marjan Jahangiri

Open access · bronzeAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in BMJ case reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
0.3field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 6 citations in OpenAlex.

  1. Pooled it
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Alessandro VivianoDepartment of Cardiothoracic Surgery, St George's University Hospital NHS Foundation Trust, London, UK.
Duncan SteeleDepartment of Cardiac Surgery, St George's Hospital, London, UK.
Mark EdsellDepartment of Cardiac Surgery, St George's Hospital, London, UK.
Marjan JahangiriDepartment of Cardiac Surgery, St George's Hospital, London, UK.
St George's Hospital · GBSt George’s University Hospitals NHS Foundation Trust · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We present a case of massive perioperative bleeding due to severe coagulopathy following urgent aortic and mitral valve replacement. Bleeding was persistent despite prolonged and meticulous surgical haemostasis and required high-volume blood products transfusions. No obvious cause was found to justify the severity of the coagulopathy, which was later attributed to high preoperative intake of ginseng.This case highlights the powerful activity of certain over-the-counter remedies on haemostasis, in this particular case on coagulation status. This also reminds us the paramount importance of a sound and comprehensive drug history for surgical patients.

Indexed as

AgedBlood Coagulation DisordersFemaleHeart Valve Prosthesis ImplantationHumansPanaxPostoperative ComplicationsPostoperative HemorrhageCardio thoracic surgeryContraindications and precautionsDrugs and medicinesHaematologyPharmacology and therapeutics

Identifiers

PMID28784871
PMCPMC5612204
OpenAlexW2754222426

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.