Evidence map›Paper›PMID 28784589›Full record

ReviewArchives of biochemistry and biophysics2017

Flavin-N5-oxide: A new, catalytic motif in flavoenzymology.

Sanjoy Adak, Tadhg P Begley

Abstract readReview
In one paragraph

Review in Archives of biochemistry and biophysics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Modulating Enzyme FunctionFrontiers in molecular biosciences · 2021
    Article
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Sanjoy AdakDepartment of Chemistry, Texas A&M University, College Station, TX 77843, United States.
Tadhg P BegleyDepartment of Chemistry, Texas A&M University, College Station, TX 77843, United States. Electronic address: Begley@tamu.edu.

Funding

The mechanistic enzymology of thiamin biosynthesisR01DK044083 · NIDDK · CORNELL UNIVERSITY ITHACA · PI BEGLEY, TADHG P. · 1991 to 2007
$2.5M
NIDDK NIH HHS R01 DK044083
6 · The paper itself

Abstract

Flavin-N5-oxide is a recently discovered intermediate used by EncM (1,3-diketone oxidation), DszA (sulfone monooxygenase) and RutA (amide monooxygenase). This review describes the mechanism of these enzymes and proposes criteria for the identification of additional Flavin-N5-oxide dependent enzymes.

Indexed as

Amino Acid MotifsCatalysisFlavinsFlavoproteinsMixed Function OxygenasesFlavinsFlavoproteinsMixed Function Oxygenases

Identifiers

PMID28784589
PMCPMC6037421

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.