Evidence map›Paper›PMID 28784159›Full record

ArticleItalian journal of pediatrics2017

Epidemiological and clinical peculiarities of polyglandular syndrome type 3 in pediatric age.

Mariella Valenzise, Tommaso Aversa, Angiola Saccomanno, Filippo De Luca, Giuseppina Salzano

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Article in Italian journal of pediatrics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Mariella ValenziseUOC Pediatria, Department of Human Pathology in Adulthood and Childhood, University of Messina, via Consolare Valeria, 98125, Messina, Italy. mvalenzise@unime.it.
Tommaso AversaUOC Pediatria, Department of Human Pathology in Adulthood and Childhood, University of Messina, via Consolare Valeria, 98125, Messina, Italy.
Angiola SaccomannoUOC Pediatria, Department of Human Pathology in Adulthood and Childhood, University of Messina, via Consolare Valeria, 98125, Messina, Italy.
Filippo De LucaUOC Pediatria, Department of Human Pathology in Adulthood and Childhood, University of Messina, via Consolare Valeria, 98125, Messina, Italy.
Giuseppina SalzanoUOC Pediatria, Department of Human Pathology in Adulthood and Childhood, University of Messina, via Consolare Valeria, 98125, Messina, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAlthough the autoimmune polyglandular syndrome type 3 (APS-3) is the commonest APS that may be encountered in pediatric age, last year literature includes only few studies aiming to specifically ascertain the clinical spectrum of APS-3 in childhood and adolescence. Aims of these study were: a) to ascertain how many young patients with apparently isolated Hashimoto's thyroiditis (HT) are at risk of manifesting other autoimmune disorders (ADs) compatible with APS-3; b) to individuate the ADs which most frequently segregate with HT in the context of an APS-3.

methodsA selected population of 211 young patients with HT and no risk factors for other APSs was investigated, in order to evaluate the prevalence of other ADs apart from HT and to individuate the ADs which most frequently cluster with HT in the context of APS-3.

resultsThe majority of our patients (70.2%) was found to be affected by no other ADs apart from HT, whereas the remaining 29.8% were classified as affected by an APS-3. The ADs which were found most frequently in aggregation with HT were type 1 diabetes mellitus T1DM (61.9%) and celiac disease CD (22.2%).

conclusions1) About 30% of young patients with HT may exhibit a clinical picture consistent with APS-3; 2) In the context of APS-3 the ADs that most frequently cluster with HT are T1DM and CD.

Indexed as

Age DistributionCeliac DiseaseChildChild, PreschoolCluster AnalysisCross-Sectional StudiesDiabetes Mellitus, Type 1Diagnosis, DifferentialFemaleHashimoto DiseaseHumansMalePolyendocrinopathies, AutoimmunePrevalencePrognosisRisk AssessmentCeliac diseaseHashimoto’s thyroiditisType 1 diabetes mellitus

Identifiers

PMID28784159
PMCPMC5545841

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.