Evidence map›Paper›PMID 28783666›Full record

ArticleScience immunology2017

Dynamics of influenza-induced lung-resident memory T cells underlie waning heterosubtypic immunity.

Bram Slütter, Natalija Van Braeckel-Budimir, Georges Abboud, Steven M Varga, Shahram Salek-Ardakani, John T Harty

Abstract read
In one paragraph

Article in Science immunology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 211 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
211citing papers in PubMed, 1 pooled it
13.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

211 citing papers in PubMed, 1 synthesis or guideline pooled it, 294 citations in OpenAlex.

  1. Mucosal immunity and vaccine development.Signal transduction and targeted therapy · 2026
    Pooled it
  2. Innate-like Gene Expression of Lung-Resident Memory CD8American journal of respiratory and critical care medicine · 2021
    Trial
  3. Article
  4. Monocyte-derived galectin-1Nature immunology · 2026
    Article
  5. Article
  6. Review
  7. Article
  8. CD8MedComm · 2026
    Review
  9. Review
  10. Article
  11. Review
  12. Article
  13. Review
  14. CD27 and ICOS as Targets of PD-1/PD-L1 Signaling to Regulate Resident Memory CD8Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  15. Article
  16. Review
  17. Article
  18. Article
  19. Article
  20. Review

151 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Bram SlütterDepartment of Microbiology, University of Iowa, Iowa City, IA 52242, USA.
Natalija Van Braeckel-BudimirDepartment of Microbiology, University of Iowa, Iowa City, IA 52242, USA.
Georges AbboudDepartment of Pathology, Immunology and Laboratory Medicine, University of Florida, Gainesville, FL 32611, USA.
Steven M VargaDepartment of Microbiology, University of Iowa, Iowa City, IA 52242, USA.
Shahram Salek-ArdakaniDepartment of Pathology, Immunology and Laboratory Medicine, University of Florida, Gainesville, FL 32611, USA.
John T HartyDepartment of Microbiology, University of Iowa, Iowa City, IA 52242, USA. john-harty@uiowa.edu.
University of Iowa · USUniversity of Florida · US

Funding

Regulation of primary and secondary CD4 and CD8 T cell memoryR37AI042767 · NIAID · UNIVERSITY OF IOWA · PI HARTY, JOHN T · 2008 to 2017
$4.7M
Memory CD8 T cell localization and protection from influenzaR01AI114543 · NIAID · UNIVERSITY OF IOWA · PI BADOVINAC, VLADIMIR P, HARTY, JOHN T · 2015 to 2024
$4.4M
T resident memory in the lungR01AI042767 · NIAID · UNIVERSITY OF IOWA · PI HARTY, JOHN T · 1998 to 2023
$4.4M
CD8+ T Cell effector mechanisms against L. monocytogenesR21AI042767 · NIAID · UNIVERSITY OF IOWA · PI HARTY, JOHN T. · 2002 to 2002
$331k
NIAID NIH HHS R01 AI042767NIAID NIH HHS R01 AI114543NIAID NIH HHS R21 AI042767NIAID NIH HHS R37 AI042767
6 · The paper itself

Abstract

Lung-resident memory CD8 T cells (T

Identifiers

PMID28783666
PMCPMC5590757
OpenAlexW2569985415

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.