Evidence map›Paper›PMID 28783102›Full record

ReviewChildren (Basel, Switzerland)2017

The Pulmonary Circulation in the Single Ventricle Patient.

Amanda Hauck, Nicolas Porta, Steven Lestrud, Stuart Berger

Open access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Children (Basel, Switzerland), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 36 citations in OpenAlex.

  1. Review
  2. Long-term survival and complications of Fontan patients: where do we stand?American journal of cardiovascular disease · 2026
    Review
  3. Article
  4. The single ventricle presenting late: surgical options.Indian journal of thoracic and cardiovascular surgery · 2025
    Review
  5. Endothelial dysfunction in single ventricle physiology and the Fontan circulation - What lies ahead.International journal of cardiology. Congenital heart disease · 2025
    Review
  6. Review
  7. Article
  8. Article
  9. Review
  10. Review
  11. Review
  12. Article
  13. Article
  14. Review
  15. Observational
  16. Article
  17. Balancing a single-ventricle circulation: 'physiology to therapy'.Indian journal of thoracic and cardiovascular surgery · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Amanda HauckDivisions of Neonatology, Pediatric Pulmonary Medicine and Pediatric Cardiology, Northwestern University Medical School, Lurie Children' Hospital, 225 E, Chicago Avenue, Chicago, IL 60622, USA. ahauck@luriechildrens.org.
Nicolas PortaDivisions of Neonatology, Pediatric Pulmonary Medicine and Pediatric Cardiology, Northwestern University Medical School, Lurie Children' Hospital, 225 E, Chicago Avenue, Chicago, IL 60622, USA. n-porta@northwestern.edu.
Steven LestrudDivisions of Neonatology, Pediatric Pulmonary Medicine and Pediatric Cardiology, Northwestern University Medical School, Lurie Children' Hospital, 225 E, Chicago Avenue, Chicago, IL 60622, USA. slestrud@luriechildrens.org.
Stuart BergerDivisions of Neonatology, Pediatric Pulmonary Medicine and Pediatric Cardiology, Northwestern University Medical School, Lurie Children' Hospital, 225 E, Chicago Avenue, Chicago, IL 60622, USA. stberger@luriechildrens.org.
Northwestern University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In recent decades, survival of children with complex congenital heart disease has improved considerably. Specifically, children with a variety of congenital heart defects resulting in 'single ventricle' physiology can now undergo palliative surgery that allows survival beyond the neonatal period, and in many cases into adulthood, despite having a single functional ventricular pumping chamber supplying both the pulmonary and systemic circulation. Our growing understanding of the functionally univentricular heart has resulted in freedom from Fontan failure of >50% at 25 years post-Fontan. Yet there is still a fair amount of knowledge to be gained, specifically as it relates to the pulmonary circulation in this group of patients. Knowledge gaps relate not only to the pulmonary circulation after Fontan operation, but also at each stage of the single ventricle surgical palliation, including the native physiology prior to any intervention. The pulmonary circulation is affected by multiple issues related to the single ventricle, including specific details of the anatomy unique to each patient, any intervention(s) undertaken, and potential complications such as aortopulmonary collaterals, protein losing enteropathy, plastic bronchitis, venovenous collaterals, pulmonary arteriovenous fistulae, ventricular dysfunction, pulmonary venous stenosis, and more. This chapter will review the current knowledge with regard to the pulmonary circulation in the single ventricle patient, primarily after the Fontan operation. Additionally, it is our hope to help the practitioner assess the pulmonary circulation in the single ventricle patient; we will also discuss the evidence behind and approach to treatment strategies in order to optimize the pulmonary circulation in this complex group of patients.

Indexed as

Fontanpulmonary vascular bedsingle ventricle

Identifiers

PMID28783102
PMCPMC5575593
OpenAlexW2742960218

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.