ReviewProteomes2017
Role of Salivary Biomarkers in Detection of Cardiovascular Diseases (CVD).
Review in Proteomes, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
33 citing papers in PubMed, 72 citations in OpenAlex.
- Clinical Treatment Analysis and Imaging Study of Patients with Acute Angina in Cardiovascular Medicine.Journal of healthcare engineering · 2021Trial
- Salivary Proteome Role in Infection and Immunity.Advances in experimental medicine and biology · 2026Review
- Saliva metabolomics: a non-invasive frontier for diagnosing and managing oral diseases.Journal of translational medicine · 2025Review
- Natural and induced immune responses in oral cavity and saliva.BMC immunology · 2025Review
- Rapid diagnosis of different cardiovascular disease events from early released cardiac biomarkers, cTnI, BNP, and CRP, by biosensor technology.Frontiers in cardiovascular medicine · 2025Article
- Review
- The Role of Oral Biomarkers in the Assessment of Noncommunicable Diseases.Diagnostics (Basel, Switzerland) · 2024Review
- Proteomic profiling of extracellular vesicles derived from human serum for the discovery of biomarkers in Avascular necrosis.Clinical proteomics · 2024Article
- The Potential Role of Salivary NT-proBNP in Heart Failure.Life (Basel, Switzerland) · 2023Article
- Periodontitis and cardiovascular risk factors in subjects with and without type 1 diabetes: A cross sectional analysis.Journal of diabetes and its complications · 2023Article
- Salivary biomarkers: novel noninvasive tools to diagnose chronic inflammation.International journal of oral science · 2023Review
- Aptamers Targeting Cardiac Biomarkers as an Analytical Tool for the Diagnostics of Cardiovascular Diseases: A Review.Biomedicines · 2022Review
- Non-Invasive Assessment of Congestion by Cardiovascular and Pulmonary Ultrasound and Biomarkers in Heart Failure.Diagnostics (Basel, Switzerland) · 2022Review
- Biology of Cardiac Troponins: Emphasis on Metabolism.Biology · 2022Review
- Microfluidic Point-of-Care (POC) Devices in Early Diagnosis: A Review of Opportunities and Challenges.Sensors (Basel, Switzerland) · 2022Review
- Metabolic Pathway of Cardiospecific Troponins: From Fundamental Aspects to Diagnostic Role (Comprehensive Review).Frontiers in molecular biosciences · 2022Review
- The Importance of Cardiac Troponin Metabolism in the Laboratory Diagnosis of Myocardial Infarction (Comprehensive Review).BioMed research international · 2022Review
- Dental Healthcare Amid the COVID-19 Pandemic.International journal of environmental research and public health · 2021Review
- Serum-Derived Neuronal Exosomal miRNAs as Biomarkers of Acute Severe Stress.International journal of molecular sciences · 2021Article
- Differential Glycosylation Levels in Saliva from Patients with Lung or Breast Cancer: A Preliminary Assessment for Early Diagnostic Purposes.Metabolites · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Human whole mouth saliva (WMS) is secreted by salivary glands, namely parotid, submandibular/sublingual and other minor glands of the oral cavity. It is secreted in a systematic way, and contain informative proteins and peptides for the early detection of contagious diseases and organ-related diseases. The role of WMS as a liquid biopsy for the detection of cardiovascular diseases (CVD) through Myoglobin (MYO), Cardiac troponin I (cTnI), Creatine phosphokinase MB (CK-MB), Myeloperoxidase (MPO), brain natriuretic peptide (NT-proBNP), Exosomal miRNA, C-Reactive Protein (CRP), Matrix metalloproteinase-8 (MMP-8), MMP-9 and tissue inhibitor of MMP-8 (TIMP-1), leukotriene B4 has been well reported in last decade, that have been reviewed in the literature comprehensively below.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.