Evidence map›Paper›PMID 28783063›Full record

ArticleBiosensors2017

An Affordable Microsphere-Based Device for Visual Assessment of Water Quality.

Azra Rajwani, Brendon Restall, Nathan J Muller, Scott Roebuck, Stephanie M Willerth

Abstract read
In one paragraph

Article in Biosensors, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Azra RajwaniBiomedical Engineering program, University of Victoria, Victoria, BC V8W 2Y2, Canada. azra.rajwani@gmail.com.
Brendon RestallBiomedical Engineering program, University of Victoria, Victoria, BC V8W 2Y2, Canada. brestall@uvic.ca.
Nathan J MullerDepartment of Mechanical Engineering, University of Victoria, Victoria, BC V8W 2Y2, Canada. mullernathan@gmail.com.
Scott RoebuckDivision of Medical Sciences, University of Victoria, Victoria, BC V8W 2Y2, Canada. sroebuck@uvic.ca.
Stephanie M WillerthDepartment of Mechanical Engineering, University of Victoria, Victoria, BC V8W 2Y2, Canada. willerth@uvic.ca.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This work developed a prototype of an affordable, long-term water quality detection device that provides a visual readout upon detecting bacterial contamination. This device prototype consists of: (1) enzyme-releasing microspheres that lyse bacteria present in a sample, (2) microspheres that release probes that bind the DNA of the lysed bacteria, and (3) a detector region consisting of gold nanoparticles. The probes bind bacterial DNA, forming complexes. These complexes induce aggregation of the gold nanoparticles located in the detector region. The nanoparticle aggregation process causes a red to blue color change, providing a visual indicator of contamination being detected. Our group fabricated and characterized microspheres made of poly (ε-caprolactone) that released lysozyme (an enzyme that degrades bacterial cell walls) and hairpin DNA probes that bind to regions of the

Indexed as

MicrospheresWater MicrobiologyWater QualityBiosensing TechniquesColorimetryCosts and Cost AnalysisDNA, BacterialEscherichia coliGoldMetal NanoparticlesMuramidasePolyestersDNA, BacterialGoldMuramidasepolycaprolactonePolyesterscolorimetric assaydrug deliveryglobal healthmicrospheresnanoparticleswater quality

Identifiers

PMID28783063
PMCPMC5618037

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.