Evidence map›Paper›PMID 28782560›Full record

ArticleJournal of molecular biology2017

Glutamate promotes SSB protein-protein Interactions via intrinsically disordered regions.

Alexander G Kozlov, Min Kyung Shinn, Elizabeth A Weiland, Timothy M Lohman

Open access · greenAbstract read
In one paragraph

Article in Journal of molecular biology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
3.0field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 57 citations in OpenAlex.

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  5. Generation and Repair of Postreplication Gaps in Escherichia coli.Microbiology and molecular biology reviews : MMBR · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Alexander G KozlovDepartment of Biochemistry and Molecular Biophysics, Washington University School of Medicine, 660 S. Euclid Ave., St. Louis, MO 63110, United States.
Min Kyung ShinnDepartment of Biochemistry and Molecular Biophysics, Washington University School of Medicine, 660 S. Euclid Ave., St. Louis, MO 63110, United States; Department of Physics, Washington University in St. Louis, St. Louis, MO 63130, United States.
Elizabeth A WeilandDepartment of Biochemistry and Molecular Biophysics, Washington University School of Medicine, 660 S. Euclid Ave., St. Louis, MO 63110, United States.
Timothy M LohmanDepartment of Biochemistry and Molecular Biophysics, Washington University School of Medicine, 660 S. Euclid Ave., St. Louis, MO 63110, United States. Electronic address: lohman@wustl.edu.
Washington University in St. Louis · US

Funding

SSB PROTEIN/DNA INTERACTIONSR01GM030498 · NIGMS · WASHINGTON UNIVERSITY · PI LOHMAN, TIMOTHY M · 1985 to 2019
$7.4M
NIGMS NIH HHS R01 GM030498
6 · The paper itself

Abstract

E. coli single strand (ss) DNA binding protein (SSB) is an essential protein that binds to ssDNA intermediates formed during genome maintenance. SSB homotetramers bind ssDNA in several modes that differ in occluded site size and cooperativity. High "unlimited" cooperativity is associated with the 35 site size ((SSB)

Indexed as

Protein MultimerizationDNA-Binding ProteinsEscherichia coliEscherichia coli ProteinsGlutamic AcidModels, BiologicalModels, ChemicalProtein BindingDNA-Binding ProteinsEscherichia coli ProteinsGlutamic AcidSSB protein, E colicooperativityHofmeisterIDPpreferential hydrationSSB-ssDNA interactions

Identifiers

PMID28782560
PMCPMC5576569
OpenAlexW2744835540

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.