Evidence map›Paper›PMID 28782559›Full record

ArticleJournal of molecular biology2017

Trap

Cristina Mayor-Ruiz, Orlando Dominguez, Oscar Fernandez-Capetillo

Open access · greenAbstract read
In one paragraph

Article in Journal of molecular biology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.4field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Article
  6. Applications ofStem cells international · 2021
    Review
  7. Article
  8. Article
  9. Targeting ATR in cancer.Nature reviews. Cancer · 2018
    Review
  10. New tools for old drugs: Functional genetic screens to optimize current chemotherapy.Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy · 2018
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Cristina Mayor-RuizGenomic Instability Group, Spanish National Cancer Research Centre, 28029 Madrid, Spain.
Orlando DominguezGenomics Unit, Spanish National Cancer Research Centre, 28029 Madrid, Spain.
Oscar Fernandez-CapetilloGenomic Instability Group, Spanish National Cancer Research Centre, 28029 Madrid, Spain; Science for Life Laboratory, Division of Genome Biology, Department of Medical Biochemistry and Biophysics, Karolinska Institute, 171 21 Stockholm, Sweden. Electronic address: ofernandez@cnio.es.
Spanish National Cancer Research Centre · ESKarolinska Institutet · SE

Funding

European Research Council 617840
6 · The paper itself

Abstract

The development of haploid mammalian cell lines, coupled to next-generation sequencing, has recently facilitated forward genetic screenings in mammals. For mutagenesis, retrovirus- or transposon-based gene traps are frequently used. Current methods to map gene-trap insertions are based on inverse or splinkerette PCR, which despite their efficacy are prone to artifacts and do not provide information on expression of the targeted gene. Here, we describe a new RNA sequencing-based method (Trap

Indexed as

AnimalsCost-Benefit AnalysisHigh-Throughput Nucleotide SequencingHumansMutagenesis, InsertionalSequence Analysis, RNATime Factorsgenetic screeningsGene traphaploid mammalian cellspiggyBac transposonRNAseq

Identifiers

PMID28782559
PMCPMC5695663
OpenAlexW2742832192

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.