Evidence map›Paper›PMID 28782510›Full record

ArticleJournal of invertebrate pathology2017

Contributions of 5'-UTR and 3'-UTR cis elements to Cyt1Aa synthesis in Bacillus thuringiensis subsp. israelensis.

Yuko Sakano, Hyun-Woo Park, Dennis K Bideshi, Baoxue Ge, Brian A Federici

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of invertebrate pathology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Article
  3. Can (We Make)Toxins · 2021
    Review
  4. How DoesToxins · 2021
    Review
  5. Article
  6. Chitinases ofFrontiers in microbiology · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Yuko SakanoDepartment of Entomology, University of California, Riverside, Riverside, CA 92521, United States.
Hyun-Woo ParkDepartment of Entomology, University of California, Riverside, Riverside, CA 92521, United States; Department of Biological Sciences, California Baptist University, Riverside, CA 92504, United States. Electronic address: hpark@calbaptist.edu.
Dennis K BideshiDepartment of Entomology, University of California, Riverside, Riverside, CA 92521, United States; Department of Biological Sciences, California Baptist University, Riverside, CA 92504, United States.
Baoxue GeInterdepartmental Graduate Program in Genetics, Genomics, and Bioinformatics, University of California, Riverside, Riverside, CA 92521, United States.
Brian A FedericiDepartment of Entomology, University of California, Riverside, Riverside, CA 92521, United States; Interdepartmental Graduate Program in Genetics, Genomics, and Bioinformatics, University of California, Riverside, Riverside, CA 92521, United States.

Funding

Molecular Improvement of Bacterial Mosquito LarvicidesR01AI045817 · NIAID · UNIVERSITY OF CALIFORNIA RIVERSIDE · PI FEDERICI, BRIAN A. · 2001 to 2014
$4.5M
NIAID NIH HHS R01 AI045817
6 · The paper itself

Abstract

The biopesticide used most effectively to control mosquito and blackfly vectors of human diseases worldwide is Bacillus thuringiensis subsp. israelensis. The high efficacy of this bacterium is due to synergistic interactions among four protein entomotoxins assembled individually into a single parasporal body (PB) during sporulation. Cyt1Aa, the primary synergist, is the most abundant toxin, comprising approximately 55% of the PB's mass. The other proteins are Cry11Aa at ∼35%, and Cry4Aa and Cry4Ba, which together account for the remaining ∼10%. The molecular genetic basis for the comparatively large amount of Cyt1Aa synthesized is unknown. Here, in addition to the known strong BtI (σ

Indexed as

3' Untranslated Regions5' Untranslated RegionsBacillus thuringiensisBacillus thuringiensis ToxinsBacterial ProteinsEndotoxinsHemolysin ProteinsPromoter Regions, Genetic3' Untranslated Regions5' Untranslated RegionsBacillus thuringiensis ToxinsBacterial ProteinsEndotoxinsHemolysin Proteinsinsecticidal crystal protein, Bacillus Thuringiensis3′-UTR5′-UTRBacillus thuringiensis subsp. israelensiscyt1AaPromotersTranscriptional terminator

Identifiers

PMID28782510
PMCPMC5600697

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.