ReviewJournal of neuroscience research2018
Regulation of synaptic scaling by action potential-independent miniature neurotransmission.
Review in Journal of neuroscience research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed.
- Lithium as a therapeutic strategy for SNAP25 encephalopathies via modulation of homeostatic plasticity.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026Article
- Dopaminergic tone inhibits spontaneous glutamate release and augments homeostatic synaptic plasticity.Molecular psychiatry · 2026Article
- Functional Nano-segregation of Distinct Forms of Neurotransmission.Advances in neurobiology · 2026Review
- GABAergic synaptic scaling is triggered by changes in spiking activity rather than AMPA receptor activation.eLife · 2024Article
- Activation of respiratory-related bursting in an isolated medullary section from adult bullfrogs.The Journal of experimental biology · 2023Article
- Rapid homeostatic plasticity and neuropsychiatric therapeutics.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2023Review
- Nano-organization of spontaneous GABAergic transmission directs its autonomous function in neuronal signaling.Cell reports · 2022Article
- Bimodal modulation of short-term motor memory via dynamic sodium pumps in a vertebrate spinal cord.Current biology : CB · 2022Article
- Presynaptic mechanisms underlying GABACell reports · 2022Article
- Homeostatic Plasticity of the Mammalian Neuromuscular Junction.Advances in neurobiology · 2022Article
- The therapeutic potential of ultra-short-acting β-receptor antagonists in perioperative analgesic: Evidence from preclinical and clinical studies.Frontiers in pharmacology · 2022Review
- Differences in synaptic vesicle pool behavior between male and female hippocampal cultured neurons.Scientific reports · 2021Article
- Cell-type-specific synaptic imbalance and disrupted homeostatic plasticity in cortical circuits of ASD-associated Chd8 haploinsufficient mice.Molecular psychiatry · 2021Article
- Nano-Organization at the Synapse: Segregation of Distinct Forms of Neurotransmission.Frontiers in synaptic neuroscience · 2021Review
- VAMP4 Maintains a CaThe Journal of neuroscience : the official journal of the Society for Neuroscience · 2020Article
- Review
- Spontaneous and evoked neurotransmission are partially segregated at inhibitory synapses.eLife · 2020Article
- A Novel Optical Quantal Analysis of Miniature Events Reveals Enhanced Frequency Following Amyloid β Exposure.Frontiers in cellular neuroscience · 2020Article
- Competing mechanisms of plasticity impair compensatory responses to repetitive apnoea.The Journal of physiology · 2019Article
- Spontaneous neurotransmission: A form of neural communication comes of age.Journal of neuroscience research · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
Synaptic scaling represents a homeostatic adjustment in synaptic strength that was first identified as a cell-wide mechanism to achieve firing rate homeostasis after perturbations to spiking activity levels. In this review, we consider a form of synaptic scaling that is triggered by changes in action potential-independent neurotransmitter release. This plasticity appears to be both triggered and expressed locally at the dendritic site of the synapse that experiences a perturbation. A discussion of different forms of scaling triggered by different perturbations is presented. We consider work from multiple groups supporting this form of scaling, which we call neurotransmission-based scaling. This class of homeostatic synaptic plasticity is compared in studies using hippocampal and cortical cultures, as well as in vivo work in the embryonic chick spinal cord. Despite differences in the tissues examined, there are clear similarities in neurotransmission-based scaling, which appear to be molecularly distinct from the originally described spike-based scaling.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.