Evidence map›Paper›PMID 28782150›Full record

ArticleMagnetic resonance in medicine2018

MRI assessment of coronary microvascular endothelial nitric oxide synthase function using myocardial T

Sophia X Cui, Frederick H Epstein

Abstract read
In one paragraph

Article in Magnetic resonance in medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact, top 86% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Molecular Mechanisms of Adenosine Stress T1 Mapping.Circulation. Cardiovascular imaging · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Sophia X CuiBiomedical Engineering, University of Virginia, Charlottesville, Virginia, USA.ORCID 0000-0002-5133-4903
Frederick H EpsteinBiomedical Engineering, University of Virginia, Charlottesville, Virginia, USA.
University of Virginia · US

Funding

MRI of Myocardial Function in Post-Infarct Knockout MiceR01EB001763 · NIBIB · UNIVERSITY OF VIRGINIA CHARLOTTESVILLE · PI EPSTEIN, FREDERICK H · 2003 to 2020
$5.4M
94 TESLA MR SCANNER FOR MURINE IMAGING: IMAGINGS10RR019911 · NCRR · UNIVERSITY OF VIRGINIA CHARLOTTESVILLE · PI BERR, STUART S · 2005 to 2005
$2.0M
NCRR NIH HHS S10 RR019911NIBIB NIH HHS R01 EB001763
6 · The paper itself

Abstract

purposeEndothelial nitric oxide synthase (eNOS) plays a central role in regulating vascular tone, blood flow, and microvascular permeability. Endothelial dysfunction, including eNOS dysfunction, is an early biomarker of vascular disease. This study aimed to show that myocardial T

methodsWild-type mice, eNOS

resultsT

conclusionsNOS inhibition causes an increase in myocardial T

Indexed as

Magnetic Resonance ImagingAnimalsArginineBody WeightCapillary PermeabilityDiet, High-FatHeartImage Processing, Computer-AssistedMaleMiceMice, Inbred C57BLMice, KnockoutMyocardiumNG-Nitroarginine Methyl EsterNitric OxideNitric Oxide Synthase Type IIIArgininearginine methyl esterNG-Nitroarginine Methyl EsterNitric OxideNitric Oxide Synthase Type IIINos3 protein, mouseOxygencoronary endothelial functioneNOSmicrovascular permeabilitymousenitric oxide synthase inhibitionT1 mapping

Identifiers

PMID28782150
PMCPMC5803462
OpenAlexW2742960816

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.