Evidence map›Paper›PMID 28782007›Full record

ArticleScience advances2017

A modular yeast biosensor for low-cost point-of-care pathogen detection.

Nili Ostrov, Miguel Jimenez, Sonja Billerbeck, James Brisbois, Joseph Matragrano, Alastair Ager, Virginia W Cornish

Abstract read
In one paragraph

Article in Science advances, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 56 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
56citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

56 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Mining Genetically Encoded Biosensors from Filamentous Fungi.Journal of fungi (Basel, Switzerland) · 2026
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  8. A yeast mating platform for multiplex screening of fungal GPCR-ligand interactions.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Nili OstrovDepartment of Chemistry, Columbia University, New York, NY 10027, USA.ORCID 0000-0002-2157-587X
Miguel JimenezDepartment of Chemistry, Columbia University, New York, NY 10027, USA.ORCID 0000-0003-4211-1852
Sonja BillerbeckDepartment of Chemistry, Columbia University, New York, NY 10027, USA.ORCID 0000-0002-3092-578X
James BrisboisDepartment of Chemistry, Columbia University, New York, NY 10027, USA.
Joseph MatragranoDepartment of Chemistry, Columbia University, New York, NY 10027, USA.ORCID 0000-0003-4224-7266
Alastair AgerDepartment of Population and Family Health, Mailman School of Public Health, Columbia University, New York, NY 10032, USA.
Virginia W CornishDepartment of Chemistry, Columbia University, New York, NY 10027, USA.ORCID 0000-0002-5676-4718

Funding

A Household Yeast Biosensor for CholeraR01AI110794 · NIAID · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI CORNISH, VIRGINIA W · 2015 to 2019
$3.2M
NIAID NIH HHS R01 AI110794
6 · The paper itself

Abstract

The availability of simple, specific, and inexpensive on-site detection methods is of key importance for deployment of pathogen surveillance networks. We developed a nontechnical and highly specific colorimetric assay for detection of pathogen-derived peptides based on

Indexed as

Biosensing TechniquesPoint-of-Care TestingYeastsHumansMycosesReceptors, G-Protein-CoupledSaccharomyces cerevisiaeReceptors, G-Protein-Coupledbiosensorfungal pathogensG-Protein coupled receptorinvasive fungal infectionslow-cost diagnosticlycopenepeptide biomarkerpoint-of-caresynthetic biologyYeast

Identifiers

PMID28782007
PMCPMC5489263

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.