Evidence map›Paper›PMID 28781966›Full record

ArticleCanadian journal of gastroenterology & hepatology2017

Obesity Increases Prevalence of Colonic Adenomas at Screening Colonoscopy: A Canadian Community-Based Study.

Theodore F Shapero, Grant I Chen, Tim Devlin, Alison Gibbs, Iain C Murray, Stanley Tran, Corey Weigensberg

Open access · goldAbstract readMulticenter Study
In one paragraph

Article in Canadian journal of gastroenterology & hepatology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.3field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 18 citations in OpenAlex.

  1. Review
  2. Article
  3. Observational
  4. Article
  5. Article
  6. Article
  7. ARE OBESITY AND ADENOMA DEVELOPMENT ASSOCIATED AS COLORECTAL CANCER PRECURSORS?Arquivos brasileiros de cirurgia digestiva : ABCD = Brazilian archives of digestive surgery · 2020
    Article
  8. Article
  9. Review
  10. UEG Week 2019 Poster Presentations.United European gastroenterology journal · 2019
    Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Theodore F ShaperoDepartment of Medicine, The Scarborough Hospital, Scarborough, ON, Canada.ORCID 0000-0002-6229-6260
Grant I ChenDepartment of Medicine, The Scarborough Hospital, Scarborough, ON, Canada.
Tim DevlinDepartment of Medicine, The Scarborough Hospital, Scarborough, ON, Canada.
Alison GibbsDepartment of Statistical Sciences, University of Toronto, Toronto, ON, Canada.
Iain C MurrayIntestinal Health Institute, Markham, ON, Canada.
Stanley TranDepartment of Medicine, The Scarborough Hospital and North Toronto Endoscopy Clinic, Scarborough, ON, Canada.
Corey WeigensbergDepartment of Pathology, The Scarborough Hospital, Scarborough, ON, Canada.
The Scarborough Hospital · CAUniversity of Toronto · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

aimsObesity is a risk factor for colorectal neoplasia. We examined the influence of obesity and metabolic syndrome (MetS) on prevalence of neoplasia at screening colonoscopy.

methodsWe evaluated 2020 subjects undergoing first screening colonoscopy. Body mass index (BMI) was calculated at enrolment. Hyperlipidemia (HL), hypertension (HT), and diabetes mellitus (DM) were identified. Details of colonoscopy, polypectomy, and histology were recorded. Odds for adenomas (A) and advanced adenomas (ADV) in overweight (BMI 25.1-30) and obese (BMI > 30) subjects were assessed by multinomial regression, adjusted for covariates. Analyses included relationships between HL, HT, DM, age, tobacco usage, and neoplasia. Discriminatory power of HT, HL, DM, and BMI for neoplasia was assessed by binary logistic regression. Odds were calculated for neoplasia in each colonic segment related to BMI.

resultsA and ADV were commoner in overweight and obese males, obese females, older subjects, and smokers. HL, HT, and DM were associated with increased odds for neoplasia, significantly for A with hypertension. BMI alone predicted neoplasia as well as HT, HL, DM, or combinations thereof. All segments of the colon were affected. Multiple polyps were particularly prevalent in the obese.

conclusionsObesity and MetS are risk factors for colonic neoplasia in a Canadian population.

Indexed as

AdenomaAgedBody Mass IndexCanadaColonic NeoplasmsColonoscopyDiabetes MellitusFemaleHumansHyperlipidemiasHypertensionLogistic ModelsMaleMass ScreeningMetabolic SyndromeMiddle Aged

Identifiers

PMID28781966
PMCPMC5525097
OpenAlexW2734889565

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.