Evidence map›Paper›PMID 28781934›Full record

ArticleCurrent clinical microbiology reports2016

Signaling in Parasitic Nematodes: Physicochemical Communication Between Host and Parasite and Endogenous Molecular Transduction Pathways Governing Worm Development and Survival.

James B Lok

Open access · hybridAbstract read
In one paragraph

Article in Current clinical microbiology reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.6field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 28 citations in OpenAlex.

  1. Article
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  5. Review
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  8. Advances in the Molecular and Cellular Biology ofCurrent tropical medicine reports · 2019
    Article
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  10. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

James B LokDepartment of Pathobiology, School of Veterinary Medicine, University of Pennsylvania, 3800 Spruce Street, Philadelphia, PA 19104 USA.
University of Pennsylvania · US

Funding

INSULIN-LIKE SIGNALING IN PARASITIC NEMATODE DEVELOPMENTR01AI050668 · NIAID · UNIVERSITY OF PENNSYLVANIA · PI HERBERT, DE'BROSKI R · 2002 to 2023
$7.1M
Mechanisms and Treatment of Chronic, Latent Human StrongyloidiasisR33AI105856 · NIAID · UNIVERSITY OF PENNSYLVANIA · PI ABRAHAM, DAVID, LOK, JAMES B · 2015 to 2017
$1.4M
NIAID NIH HHS R01 AI050668NIAID NIH HHS R33 AI105856
6 · The paper itself

Abstract

Signaling or communication between host and parasite may occur over relatively long ranges to enable host finding and acquisition by infective parasitic nematode larvae. Innate behaviors in infective larvae transmitted from the soil that enhance the likelihood of host contact, such as negative geotaxis and hypermotility, are likely mediated by mechanoreception and neuromuscular signaling. Host cues such as vibration of the substratum, elevated temperature, exhaled CO

Indexed as

G-proteinInsulinNuclear receptorParasitic nematodeSignal transductionTGFβ

Identifiers

PMID28781934
PMCPMC5543980
OpenAlexW2528443120

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.