Evidence map›Paper›PMID 28781828›Full record

ArticleClinical case reports2017

Why could a woman have three Trisomy 21 pregnancies? - a case report.

Magda Magalhães, Cecília Marques, Fabiana Ramos, Ana Jardim, Sofia Franco, Filomena Coelho, Isabel Carreira, Paulo Moura

Open access · goldAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Clinical case reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 94% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Magda MagalhãesDepartment of Obstetrics and Gynecology A Serviço de Ginecologia e Obstetrícia Centro Hospitalar e Universitário de Coimbra Coimbra Portugal.ORCID 0000-0001-7048-8513
Cecília MarquesDepartment of Obstetrics and Gynecology A Serviço de Ginecologia e Obstetrícia Centro Hospitalar e Universitário de Coimbra Coimbra Portugal.
Fabiana RamosDepartment of Medical Genetics Hospital Pediátrico Centro Hospitalar e Universitário de Coimbra Coimbra Portugal.
Ana JardimEuropean Clinical Laboratory Geneticist Faculdade de Medicina da Universidade de Coimbra Coimbra Portugal.
Sofia FrancoDepartment of Obstetrics and Gynecology A Serviço de Ginecologia e Obstetrícia Centro Hospitalar e Universitário de Coimbra Coimbra Portugal.
Filomena CoelhoDepartment of Obstetrics and Gynecology A Serviço de Ginecologia e Obstetrícia Centro Hospitalar e Universitário de Coimbra Coimbra Portugal.
Isabel CarreiraEuropean Clinical Laboratory Geneticist Faculdade de Medicina da Universidade de Coimbra Coimbra Portugal.
Paulo MouraDepartment of Obstetrics and Gynecology A Centro Hospitalar e Universitário de Coimbra Coimbra Portugal.
Hospitais da Universidade de Coimbra · PT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mosaicism, an important cause for recurrent T21, should be suspected in families with more than one affected child wishing to receive prenatal counseling. Fluorescence in-situ hybridization analysis in a large number of cells and in different tissue samples is critical for detecting low-level mosaicism and is a key prognostic factor.

Indexed as

AneuploidyDown SyndromegonadalmosaicismTrisomy 21

Identifiers

PMID28781828
PMCPMC5538204
OpenAlexW2625183085

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.