Evidence map›Paper›PMID 28781714›Full record

ReviewGenes and environment : the official journal of the Japanese Environmental Mutagen Society2017

Generation, repair and replication of guanine oxidation products.

Katsuhito Kino, Masayo Hirao-Suzuki, Masayuki Morikawa, Akane Sakaga, Hiroshi Miyazawa

Open access · goldAbstract readReview
In one paragraph

Review in Genes and environment : the official journal of the Japanese Environmental Mutagen Society, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers.

0numbers the graph read from it
0cells of the map it votes in
51citing papers in PubMed
3.7field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

51 citing papers in PubMed, 122 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Measuring Biomarkers of Oxidative Stress in ME/CFS Patients.Methods in molecular biology (Clifton, N.J.) · 2025
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Chemical Insights into Oxidative and Nitrative Modifications of DNA.International journal of molecular sciences · 2023
    Review
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Katsuhito KinoLaboratory of Molecular Biology, Kagawa School of Pharmaceutical Sciences, Tokushima Bunri University, 1314-1, Shido, 769-2193, Sanuki, Kagawa Japan.
Masayo Hirao-SuzukiLaboratory of Xenobiotic Metabolism and Environmental Toxicology, Faculty of Pharmaceutical Sciences, Hiroshima International University (HIU), 5-1-1 Hiro-koshingai, Kure, 737-0112, Hiroshima, Japan.
Masayuki MorikawaLaboratory of Medicinal Chemistry, Kagawa School of Pharmaceutical Sciences, Tokushima Bunri University, 1314-1, Shido, 769-2193, Sanuki, Kagawa Japan.
Akane SakagaLaboratory of Molecular Biology, Kagawa School of Pharmaceutical Sciences, Tokushima Bunri University, 1314-1, Shido, 769-2193, Sanuki, Kagawa Japan.
Hiroshi MiyazawaLaboratory of Molecular Biology, Kagawa School of Pharmaceutical Sciences, Tokushima Bunri University, 1314-1, Shido, 769-2193, Sanuki, Kagawa Japan.
Tokushima Bunri University · JPHiroshima International University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Guanine is the most readily oxidized of the four DNA bases, and guanine oxidation products cause G:C-T:A and G:C-C:G transversions through DNA replication. 8-Oxo-7,8-dihydroguanine (8-oxoG) causes G:C-T:A transversions but not G:C-C:G transversions, and is more readily oxidized than guanine. This review covers four major findings. (i) 2,2,4-Triamino-5(2

Indexed as

2,2,4-triamino-5(2H)-oxazolone (oz)Base pairContiguous ozDNA polymeraseG:C-C:G transversionsGuanineHighest occupied molecular orbital (HOMO)OxidationQuadruplex DNARepair

Identifiers

PMID28781714
PMCPMC5537945
OpenAlexW2735309949

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.