Evidence map›Paper›PMID 28781594›Full record

ArticleInternational journal of endocrinology2017

Plasma lncRNA GAS8-AS1 as a Potential Biomarker of Papillary Thyroid Carcinoma in Chinese Patients.

Dongxue Zhang, Xin Liu, Bojun Wei, Guoliang Qiao, Tao Jiang, Zhenwen Chen

Open access · goldAbstract read
In one paragraph

Article in International journal of endocrinology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
2.7field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 45 citations in OpenAlex.

  1. LncRNAFrontiers in endocrinology · 2026
    Article
  2. Review
  3. Article
  4. Article
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  6. Role of LncRNA score and PVT1 in primary hyperparathyroidism-- a preliminary study.Journal of otolaryngology - head & neck surgery = Le Journal d'oto-rhino-laryngologie et de chirurgie cervico-faciale · 2021
    Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Observational
  13. Review
  14. Article
  15. Review
  16. Review
  17. Genome-wide analysis of differentially expressed lncRNA in sporadic parathyroid tumors.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2019
    Article
  18. Article
  19. GAS8 and GAS8-AS1 expression in gastric cancer.Gastroenterology and hepatology from bed to bench · 2019
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Dongxue ZhangDepartment of Endocrinology, Beijing Shijitan Hospital, Capital Medical University, Beijing 100038, China.ORCID 0000-0002-5714-7893
Xin LiuDepartment of Medical Genetics and Developmental Biology, Capital Medical University, Beijing 100069, China.ORCID 0000-0002-3449-6468
Bojun WeiDepartment of Thyroid and Neck Surgery, Beijing Chaoyang Hospital, Capital Medical University, Beijing 100020, China.ORCID 0000-0002-3633-3232
Guoliang QiaoDepartment of Medical Oncology, Beijing Shijitan Hospital, Capital Medical University, Beijing 10038, China.
Tao JiangDepartment of Endocrinology, Beijing Shijitan Hospital, Capital Medical University, Beijing 100038, China.ORCID 0000-0002-0582-3298
Zhenwen ChenDepartment of Medical Genetics and Developmental Biology, Capital Medical University, Beijing 100069, China.ORCID 0000-0003-1863-2703
Capital Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLong noncoding RNAs (lncRNAs) were recently shown to have potential in the diagnosis and prognosis for numerous cancers. lncRNA GAS8-AS1 is decreased in papillary thyroid cancer (PTC) tissue, but its plasma expression and clinical value in patients with PTC remain unknown. MATERIALS AND

methodsWe investigated the expression profile of plasma GAS8-AS1 in 97 patients with PTC and 39 patients with nodular goiter by quantitative real-time polymerase chain reaction.

resultsGAS8-AS1 expression in plasma was downregulated in patients with PTC in comparison with those in nodular goiters (

conclusionThe present study indicates that circulating GAS8-AS1 is a potential biomarker for PTC diagnosis and LNM prediction.

Identifiers

PMID28781594
PMCPMC5525075
OpenAlexW2736304919

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.